The association between birth weight at term and long-term endocrine morbidity of the offspring

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Efrat SpiegelE Sheiner

Abstract

To investigate whether small-for-gestational-age (SGA) and large-for-gestational-age (LGA) birth weight at-term poses an increased risk for long-term pediatric endocrine morbidity. A retrospective population-based cohort study compared the incidence of long-term pediatric hospitalizations due to endocrine morbidity of singleton children born SGA, appropriate-for-gestational-age (AGA), and LGA at-term. A multivariate generalized estimating equation (GEE) logistic regression model analysis was used to control for confounders. During the study period, 235,614 deliveries met the inclusion criteria; of which 4.7% were SGA (n = 11,062), 91% were AGA (n = 214,249), and 4.3% were LGA neonates (n = 10,303). During the follow-up period, children born SGA or LGA at-term had a significantly higher rate of long-term endocrine morbidity. Using a multivariable GEE logistic regression model, controlling for confounders, being delivered SGA or LGA at-term was found to be an independent risk factor for long-term pediatric endocrine morbidity (Adjusted OR = 1.4; 95%CI = 1.1-1.8; p = .015 and aOR = 1.4; 95%CI = 1.1-1.8; p = .005, respectively). Specifically, LGA was found an independent risk factor for overweight and obesity (aOR = 1.7; 95%CI = 1....Continue Reading

References

Sep 9, 1989·Lancet·D J BarkerS J Simmonds
Jul 15, 1995·BMJ : British Medical Journal·D J Barker
Jan 7, 1995·BMJ : British Medical Journal·C H FallS Duggleby
Aug 21, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·B ClaussonS Cnattingius
May 24, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·R C HuangL J Beilin
May 25, 2006·Clinical Obstetrics and Gynecology·David J P Barker
Sep 23, 2006·European Journal of Endocrinology·Jing-Yan TianMin Luo
Sep 29, 2006·Maternal and Child Health Journal·Jennifer S HuangMichael C Lu
Sep 29, 2007·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·Youfa Wang, Tim Lobstein
Jan 31, 2008·Acta Obstetricia Et Gynecologica Scandinavica·Tore Henriksen
Oct 18, 2008·Seminars in Fetal & Neonatal Medicine·Yariv Yogev, Gerard H A Visser
Nov 26, 2008·American Journal of Perinatology·Tetyana H Nesterenko, Hany Aly
Dec 26, 2008·JAMA : the Journal of the American Medical Association·Peter H WhincupDonald E Yarbrough
Nov 18, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·L Schack-NielsenT I A Sørensen
Apr 15, 2010·Neonatology·Gregory M HermannRobert D Roghair
Sep 16, 2010·Annals of the New York Academy of Sciences·Nektaria Xita, Agathocles Tsatsoulis
Apr 25, 2012·Maternal and Child Health Journal·Sara M LindbergRonald J Prince
Jun 22, 2013·Clinical Obstetrics and Gynecology·David J P Barker, Kent L Thornburg
Jan 8, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Stuart Campbell
Oct 9, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A P FrickK H Nicolaides
Oct 21, 2016·Journal of Endocrinological Investigation·C ParrinoL Frittitta

❮ Previous
Next ❯

Citations

Jan 11, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Eli NeimarkGali Pariente
Mar 21, 2021·The American Journal of Clinical Nutrition·Samrawit F YisahakStefanie N Hinkle
Jun 1, 2021·Journal of Obesity & Metabolic Syndrome·Yong Hee Hong, Ji-Eun Lee
Aug 29, 2021·Journal of Physiological Anthropology·Yuki FujitaMasayuki Iki
Dec 22, 2021·Pediatric Pulmonology·Galia PelesEyal Sheiner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Asnat WalfischEyal Sheiner
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Uri ChavkinAsnat Walfisch
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Ofir AlmasiEyal Sheiner
© 2022 Meta ULC. All rights reserved