The association between cognitive reserve and performance-related brain activity during episodic encoding and retrieval across the adult lifespan.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Abdelhalim ElshiekhM Natasha Rajah

Abstract

Remembering associations between encoded items and their contextual setting is a feature of episodic memory. Although this ability generally deteriorates with age, there is substantial variability in how older individuals perform on episodic memory tasks. A current topic of debate in the cognitive neuroscience of aging literature revolves around whether this variability may stem from genetic and/or environmental factors related to reserve, allowing some individuals to compensate for age-related decline through differential recruitment of brain regions. In this fMRI study spanning a large adult lifespan sample (N = 154), we tested whether higher cognitive reserve was associated with better task-fMRI context memory performance, and functional compensatory activity patterns in the aging brain. We used multivariate Behaviour Partial Least Squares (B-PLS) analysis to examine how age, retrieval accuracy, and a proxy measure of cognitive reserve [i.e., a composite score consisting of years of education (EDU) and crystallized IQ], impacted brain activity during the encoding and retrieval of spatial and temporal contextual details. The results indicated that age-related increases in encoding activity within anterior and lateral frontal,...Continue Reading

Citations

Nov 3, 2020·Frontiers in Neuroendocrinology·Sivaniya SubramaniapillaiGillian Einstein
Aug 12, 2021·Applied Neuropsychology. Adult·Marina Martinčević, Andrea Vranić
Dec 4, 2021·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Jennifer D RyanZhong-Xu Liu
Dec 7, 2021·Applied Neuropsychology. Adult·Carolina FeldbergRicardo Allegri

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Aging

Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.

Related Papers

Journal of the International Neuropsychological Society : JINS
Yaakov Stern
Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
Margaret H CaddenPeter A Arnett
© 2022 Meta ULC. All rights reserved