The association between early hemodynamic variables and outcome in normothermic comatose patients following cardiac arrest

Acta Anaesthesiologica Scandinavica
Christian TorgersenMartin W Dünser

Abstract

Currently, few data exist on the association between post-cardiac arrest hemodynamic function and outcome. In this explorative, retrospective analysis, the association between hemodynamic variables during the first 24 h after intensive care unit admission and functional outcome at day 28 was evaluated in 153 normothermic comatose patients following a cardiac arrest. Medical records of a multidisciplinary intensive care unit were reviewed for comatose patients (Glasgow Coma Scale < or = 9) admitted to the intensive care unit after successful resuscitation from an in- or an out-of-hospital cardiac arrest. The hourly variable time integral of hemodynamic variables during the first 24 h after admission was calculated. At day 28, outcome was assessed as favorable or adverse based on a Cerebral Performance Category of 1-2 and 3-5, respectively. Bi- and multivariate regression models adjusted for relevant confounding variables were used to evaluate the association between hemodynamic variables and functional outcome. One hundred and fifty-three normothermic comatose patients were admitted after a cardiac arrest, of whom 64 (42%) experienced a favorable outcome. Neither in the adjusted bivariate models (r(2), 0.61-0.78) nor in the adju...Continue Reading

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Citations

Sep 24, 2013·Best Practice & Research. Clinical Anaesthesiology·Kjetil Sunde
Aug 3, 2012·Journal of Veterinary Emergency and Critical Care·Benjamin M BrainardUNKNOWN RECOVER Monitoring Domain Worksheet Authors
Sep 12, 2014·Neurocritical Care·Fabio Silvio TacconeUNKNOWN Participants in the International Multi-disciplinary Consensus Conference on Multimodality Monitoring
Mar 10, 2011·Current Opinion in Anaesthesiology

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