The Association Between Heart Rate Variability and 90-Day Prognosis in Patients With Transient Ischemic Attack and Minor Stroke.

Frontiers in Neurology
Changhong LiYongjun Wang

Abstract

Background: Low heart rate variability (HRV) is known to be associated with increased all-cause, cardiovascular, and cerebrovascular mortality but its association with clinical outcomes in patients with transient ischemic attack (TIA) or minor stroke is unclear. Methods: We selected TIA and minor stroke patients from a prospective registration study. From each continuous electrocardiograph (ECG) record, each QRS complex was detected and normal-to-normal (N-N) intervals were determined. The standard deviation of all N-N intervals (SDNN) and the square root of the mean squared differences of successive N-N intervals (RMSSD) were calculated. Logistic regression analysis and Cox regression analysis were performed to assess the outcomes of patients at 90 days, and the odds and risk ratios (OR/HR) of each index quartile were compared. Results: Compared with SDNN patients in the lowest quartile, neurological disability was significantly reduced in other quartile groups at 90 days, with significant differences [OR of group Q2 was 0.659; 95% confidence interval (CI), 0.482-0.900; p = 0.0088; OR of group Q3 was 0.662; 95% CI, 0.478-0.916; p = 0.0127; OR of group Q4 was 0.441; 95% CI, 0.305-0.639; p <0.0001]. Compared with the lowest quar...Continue Reading

References

Jan 9, 2001·JAMA : the Journal of the American Medical Association·S C JohnstonS Sidney
Feb 13, 2001·European Journal of Haematology·R von Känel, J E Dimsdale
Jul 13, 2002·Cardiac Electrophysiology Review·Federico Lombardi
Jul 12, 2003·Stroke; a Journal of Cerebral Circulation·J K LovettP M Rothwell
Feb 7, 2004·Stroke; a Journal of Cerebral Circulation·Kate HardieCraig Anderson
Jun 7, 2005·Expert Opinion on Pharmacotherapy·Hans-Christoph DienerPierre Savi
Nov 18, 2006·Medical & Biological Engineering & Computing·U Rajendra AcharyaJasjit S Suri
Jun 16, 2007·Stroke; a Journal of Cerebral Circulation·Jane ProsserUNKNOWN VISTA Investigators
Jul 31, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A BassiC Caltagirone
Nov 4, 2008·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Robert G RobinsonCarlo Caltagirone
Oct 28, 2010·American Journal of Physiology. Endocrinology and Metabolism·Ya-Yu WangWayne Huey-Herng Sheu
Jan 29, 2011·Stroke; a Journal of Cerebral Circulation·Arvind ChandrathevaPeter M Rothwell
Mar 3, 2011·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Cletus CheyuoPing Wang
Jul 15, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Lu WangGerhard Litscher
Sep 17, 2011·Stroke; a Journal of Cerebral Circulation·Mustafa BalkayaMatthias Endres
Sep 17, 2011·Stroke; a Journal of Cerebral Circulation·Zeynep BiniciAhmad Sajadieh
Jun 12, 2013·Journal of Hypertension·Beata GraffKrzysztof Narkiewicz
Aug 8, 2013·Stroke; a Journal of Cerebral Circulation·Ramon Luengo-FernandezUNKNOWN Oxford Vascular Study
Nov 13, 2013·Stress : the International Journal on the Biology of Stress·Simon F StämpfliFelix C Tanner
Dec 30, 2014·Journal of the Neurological Sciences·Sylvie De RaedtJacques De Keyser
Jan 30, 2016·Journal of Cardiovascular Pharmacology and Therapeutics·Dandan WangCongxin Huang
Apr 21, 2016·The New England Journal of Medicine·Pierre AmarencoUNKNOWN TIAregistry.org Investigators
Apr 12, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Li XiongLawrence Ka Sing Wong
Oct 7, 2017·American Journal of Hypertension·Adina Zeki Al HazzouriKristine Yaffe
Oct 13, 2017·Annals of Neurology·Michael BieberChristoph Kleinschnitz
Jan 13, 2018·Journal of Neurology·Lukas MayerUNKNOWN Austrian Stroke Unit Collaborators
Oct 13, 2018·Neuroscience Bulletin·Jun MoJohn H Zhang
Jul 13, 2019·Neurology·Brett CucchiaraS Claiborne Johnston

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.