Abstract
High-sensitivity C-reactive protein (hsCRP) is associated with metabolic risk, however it is unclear whether the relationship is confounded by racial/ethnic differences in socioeconomic status (SES), lifestyle factors or central adiposity. The aims of the study was, (1) to investigate whether hsCRP levels differ by race/ethnicity; (2) to examine the race/ethnic-specific associations between hsCRP, HOMA-IR and serum lipids [total cholesterol (TC), triglycerides (TG), high-density lipoproteins (HDL-C) and low-density lipoproteins (LDL-C)]; and (3) to determine whether race/ethnic-specific associations are explained by SES, lifestyle factors or waist circumference (WC). The convenience sample comprised 195 black and 153 white apparently health women, aged 18-45 years. SES (education, assets and housing density) and lifestyle factors (alcohol use, physical activity and contraceptive use) were collected by questionnaire. Weight, height and WC were measured, and fasting blood samples collected for hsCRP, glucose, insulin, and lipids. Black women had higher age- and BMI-adjusted hsCRP levels than white women (p = 0.047). hsCRP was associated with HOMA-IR (p < 0.001), TG (p < 0.001), TC (p < 0.05), HDL-C (p < 0.05), and LDL-C (p < 0.05...Continue Reading
References
Jul 1, 1985·Diabetologia·D R MatthewsR C Turner
Jan 29, 2003·Circulation·Paul M RidkerNader Rifai
Jan 29, 2003·Circulation·Michelle A AlbertPaul M Ridker
Mar 24, 2004·Annals of Epidemiology·Demosthenes B PanagiotakosChristodoulos Stefanadis
Mar 29, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Annemarie KosterUNKNOWN Health ABC Study
Jun 10, 2006·The American Journal of Clinical Nutrition·Jennifer A NettletonDavid R Jacobs
Mar 8, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·E C RushL D Plank
Sep 12, 2007·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·A E Schutte, A Olckers
Apr 2, 2008·Obstetrics and Gynecology·Sabina CauciSecondo Guaschino
Jan 24, 2009·Scandinavian Journal of Public Health·Michelle SchneiderRia Laubscher
Feb 7, 2009·Diabetes Care·Julia H GoedeckeNaomi S Levitt
Mar 21, 2009·Obesity·Julia H GoedeckeSteven E Kahn
Nov 3, 2009·The British Journal of Nutrition·Courtney L JenningsJulia H Goedecke
Jan 28, 2010·Journal of Physical Activity & Health·Fiona C BullTimothy Armstrong
Feb 17, 2010·Metabolic Syndrome and Related Disorders·Stacey A ZenoMerrily Poth
Mar 23, 2011·Diabetes·Alain VeilleuxAndré Tchernof
Apr 30, 2011·Obesity·Gordon FisherBarbara A Gower
May 24, 2011·Metabolic Syndrome and Related Disorders·Juliet EvansJulia H Goedecke
Mar 27, 2012·Metabolism: Clinical and Experimental·Unab I KhanRachel P Wildman
Aug 14, 2012·Brain, Behavior, and Immunity·Denise Janicki DevertsKaren A Matthews
Oct 5, 2012·The New England Journal of Medicine·UNKNOWN Emerging Risk Factors CollaborationJohn Danesh
Oct 17, 2012·Molecular Aspects of Medicine·Mi-Jeong LeeSusan K Fried
Nov 22, 2012·The British Journal of Nutrition·Keigan M Park, Victor L Fulgoni
Feb 13, 2013·Journal of Obesity·Julia H GoedeckeDheshnie Keswell
Sep 17, 2013·Current Diabetes Reports·Elias K Spanakis, Sherita Hill Golden
Feb 14, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y MorimotoG Maskarinec
May 24, 2014·Nature Reviews. Drug Discovery·Marc Y Donath
Jun 4, 2014·Diabetologia·Julia OttenTommy Olsson
Jan 2, 2015·Nutrition & Metabolism·Liyun WangAnne E Sumner
Apr 13, 2015·Atherosclerosis·Nicole EllmanJulia H Goedecke
Aug 2, 2015·Diabetologia·Julia H GoedeckeTommy Olsson
Sep 26, 2015·Nutrients·Zandile J MchizaEdelweiss Wentzel-Viljoen
Feb 9, 2016·Social Science & Medicine·Katrina M WalsemannDeeonna Farr
Feb 13, 2016·Heart·Axel C CarlssonKristina Sundquist
Jun 15, 2016·Free Radical Research·Maserame Cleopatra MokhaneliCatharina Martha C Mels
Jan 27, 2017·Circulation·Emelia J BenjaminUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Jan 31, 2017·Primary Care Diabetes·Andre Pascal KengneTandi E Matsha
Apr 4, 2017·Diabetes & Metabolic Syndrome·Hamid ZandFarnush Naghashian
Apr 25, 2017·Diabetes Research and Clinical Practice·K OgurtsovaL E Makaroff
Oct 31, 2017·The Lancet. Diabetes & Endocrinology· The Lancet Diabetes Endocrinology