The association between high-sensitivity C-reactive protein and metabolic risk factors in black and white South African women: a cross-sectional study

BMC Obesity
Cindy GeorgeJulia H Goedecke

Abstract

High-sensitivity C-reactive protein (hsCRP) is associated with metabolic risk, however it is unclear whether the relationship is confounded by racial/ethnic differences in socioeconomic status (SES), lifestyle factors or central adiposity. The aims of the study was, (1) to investigate whether hsCRP levels differ by race/ethnicity; (2) to examine the race/ethnic-specific associations between hsCRP, HOMA-IR and serum lipids [total cholesterol (TC), triglycerides (TG), high-density lipoproteins (HDL-C) and low-density lipoproteins (LDL-C)]; and (3) to determine whether race/ethnic-specific associations are explained by SES, lifestyle factors or waist circumference (WC). The convenience sample comprised 195 black and 153 white apparently health women, aged 18-45 years. SES (education, assets and housing density) and lifestyle factors (alcohol use, physical activity and contraceptive use) were collected by questionnaire. Weight, height and WC were measured, and fasting blood samples collected for hsCRP, glucose, insulin, and lipids. Black women had higher age- and BMI-adjusted hsCRP levels than white women (p = 0.047). hsCRP was associated with HOMA-IR (p < 0.001), TG (p < 0.001), TC (p < 0.05), HDL-C (p < 0.05), and LDL-C (p < 0.05...Continue Reading

References

Jan 29, 2003·Circulation·Michelle A AlbertPaul M Ridker
Mar 29, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Annemarie KosterUNKNOWN Health ABC Study
Mar 8, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·E C RushL D Plank
Sep 12, 2007·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·A E Schutte, A Olckers
Jan 24, 2009·Scandinavian Journal of Public Health·Michelle SchneiderRia Laubscher
Jan 28, 2010·Journal of Physical Activity & Health·Fiona C BullTimothy Armstrong
Feb 17, 2010·Metabolic Syndrome and Related Disorders·Stacey A ZenoMerrily Poth
May 24, 2011·Metabolic Syndrome and Related Disorders·Juliet EvansJulia H Goedecke
Mar 27, 2012·Metabolism: Clinical and Experimental·Unab I KhanRachel P Wildman
Aug 14, 2012·Brain, Behavior, and Immunity·Denise Janicki DevertsKaren A Matthews
Oct 5, 2012·The New England Journal of Medicine·UNKNOWN Emerging Risk Factors CollaborationJohn Danesh
Feb 13, 2013·Journal of Obesity·Julia H GoedeckeDheshnie Keswell
Sep 17, 2013·Current Diabetes Reports·Elias K Spanakis, Sherita Hill Golden
Feb 14, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y MorimotoG Maskarinec
May 24, 2014·Nature Reviews. Drug Discovery·Marc Y Donath
Sep 26, 2015·Nutrients·Zandile J MchizaEdelweiss Wentzel-Viljoen
Feb 9, 2016·Social Science & Medicine·Katrina M WalsemannDeeonna Farr
Jun 15, 2016·Free Radical Research·Maserame Cleopatra MokhaneliCatharina Martha C Mels
Jan 27, 2017·Circulation·Emelia J BenjaminUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Apr 4, 2017·Diabetes & Metabolic Syndrome·Hamid ZandFarnush Naghashian
Apr 25, 2017·Diabetes Research and Clinical Practice·K OgurtsovaL E Makaroff
Oct 31, 2017·The Lancet. Diabetes & Endocrinology· The Lancet Diabetes Endocrinology

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