The association between hormone therapy use and changes in strength and body composition in early postmenopausal women

Menopause : the Journal of the North American Menopause Society
Gianni F MaddalozzoChristine M Snow

Abstract

To prospectively examine potential differences in upper- and lower-body muscle strength, lower-body power, lean muscle mass, total body fat, intra-abdominal fat, and energy expenditure (METS) variables in early postmenopausal women. Measurements were taken at baseline and 12 months. Prospective, 1-year non-randomized [self-selected hormone therapy (HT) and non-HT-replaced], longitudinal study with participation from 136 normally active, early [14.2 +/- 9.8 mo past menopause (51.1 +/- 3.0 y) mean age +/- SD] postmenopausal women. Total body fat mass, lean mass, and bone mass were assessed by dual-energy x-ray absorptiometry (Hologic), METS (6-mo activity recall questionnaire) upper- and lower-body peak force by isokinetic dynamometry (KinCom 500H, Chattex Corp.), and leg power by the Bassey Power Rig (Nottingham, UK). We observed no significant differences in central adipose tissue, total fat mass, lean muscle mass, strength, or lower limb power. However, estrogen did promote a maintenance affect in bone mineral density at the spine and total hip and an increase in greater trochanter bone mineral density (P < 0.01) in the estrogen-replaced group. Our findings suggest that HT does not play a role in either increasing or maintaini...Continue Reading

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Citations

Jun 30, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Sarah M GreisingGordon L Warren
Apr 7, 2007·Menopause : the Journal of the North American Menopause Society·Jeffrey J WidrickChristine Snow
Mar 19, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Philip D Chilibeck, Stephen M Cornish
Aug 22, 2009·Journal of Applied Physiology·Christina M Dieli-ConwrightE Todd Schroeder
Feb 19, 2010·Medicine and Science in Sports and Exercise·Christina M Dieli-ConwrightE Todd Schroeder
Dec 22, 2009·Sports Medicine·Deborah L Enns, Peter M Tiidus
Dec 15, 2006·Gerontology·Kimberly Y Z ForrestJane A Cauley
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Aug 30, 2005·Metabolism: Clinical and Experimental·Xin HuangBenjamin Caballero
Nov 2, 2014·Calcified Tissue International·S SipiläV Kovanen
Jan 6, 2017·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Patrick DielLars Hanke
Oct 28, 2008·The Journal of Nutrition, Health & Aging·R L KennedyV Shahsidhar

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