The association between late-life cognitive test scores and retrospective informant interview data.

International Psychogeriatrics
Riccardo E MarioniMRC Cognitive Function and Ageing Study

Abstract

Cognitive assessment of older persons, particularly those with impairment, is hampered by measurement error and the ethical issues of testing people with dementia. A potential source of valuable information about end-of-life cognitive status can be gained from those who knew the respondent well - mostly relatives or friends. This study tested the association between last cognitive assessment before death and a retrospective informant assessment of cognition. Data were analyzed from 248 participants from the Medical Research Council Cognitive Function and Ageing Study who were aged 71 to 102 years at death. Late-life cognition was assessed 0 to 8 years before death using the Mini-mental State Examination (MMSE) and the informant measure was taken 0 to 7 years after death using a Retrospective Informant Interview (RInI). Zero-inflated Poisson regression showed a strong association between MMSE scores and RInI scores - those scoring 29-30 on the MMSE had a RInI score four times lower than those who scored <18 (p < 0.001). The time between MMSE and death was also a significant predictor with each additional year increasing RInI scores by 12.4% (p < 0.001). The time between death and RInI was only a significant predictor when includ...Continue Reading

References

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Citations

Aug 26, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Ugo LuccaAngela Recchia
Feb 10, 2016·Acta Neuropathologica Communications·Stephen B WhartonUNKNOWN MRC Cognitive Function and Ageing Neuropathology Study Group
Jan 6, 2018·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Tao XuShao-Mei Han

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