The association between longer haemodialysis treatment times and hospitalization and mortality after the two-day break in individuals receiving three times a week haemodialysis

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
James FotheringhamKitty J Jager

Abstract

On the first haemodialysis (HD) day after the 2-day break in three times a week (3×W) in-centre HD, mortality and hospitalization are higher. If longer HD sessions prescribed 3×W is associated with a reduction in these events is unknown. HD session length in 19 557 prevalent European in-centre 3×W HD patients participating in the Dialysis Outcomes and Practice Patterns Study (1998-2011) were categorized into <200, 200-225, 226-250 or >250 min. Standardized event rates on the first (HD1) versus the second (HD2) HD day after the 2-day break, with supporting Cox proportional hazards models adjusted for patient and dialysis characteristics, were generated for all-cause mortality, all-cause hospitalization, out-of-hospital death and fluid overload hospitalization. By comparing HD1 with HD2, increased rates of all endpoints were observed (all P < 0.002). As HD session lengthened across the four groups, all-cause mortality per 100 patient-years on the HD1 (23.0, 20.4, 16.4 and 14.6) and HD2 (26.1, 13.3, 13.4 and 12.1) reduced. Similar improvements were observed for out-of-hospital death but were less marked for hospitalization endpoints. However, even patients dialysing >250 min were at significantly greater risk on HD1 when compared ...Continue Reading

References

Aug 3, 2000·International Journal of Epidemiology·S Greenland
Oct 11, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Riccardo Maria FagugliUmberto Buoncristiani
Aug 6, 2005·European Journal of Epidemiology·D R WitteA W Hoes
Apr 10, 2009·Clinical Journal of the American Society of Nephrology : CJASN·James O BurtonChristopher W McIntyre
Jan 22, 2010·Kidney International·Steven M BrunelliRavi Thadhani
Jan 30, 2010·Quality & Safety in Health Care·Paul AylinD Bell
Sep 3, 2010·Kidney International·Patrick H PunJohn P Middleton
Oct 12, 2010·Kidney International·Jennifer E FlytheSteven M Brunelli
Jun 11, 2011·The European Respiratory Journal·R BarbaJ Canora
Oct 14, 2011·The New England Journal of Medicine·Robert N FoleyAllan J Collins
Mar 21, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesca TentoriBruce Robinson
Aug 21, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rathika KrishnasamyDavid W Johnson
Sep 28, 2012·Kidney International·Jennifer E FlytheSteven M Brunelli
Jun 14, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Johanna KuipersCasper F M Franssen
Jun 27, 2013·Kidney International·Bruce M RobinsonRonald L Pisoni
Jun 7, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Jennifer E FlytheGary C Curhan
Apr 13, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael V RoccoUNKNOWN FHN Trial Group
Apr 30, 2015·Kidney International·Kai-Uwe EckardtUNKNOWN ARO Steering Committee
Sep 1, 2015·Kidney International·Connie M Rhee, Kamyar Kalantar-Zadeh
Oct 16, 2015·Journal of the American Society of Nephrology : JASN·Glenn M ChertowUNKNOWN Frequent Hemodialysis Network (FHN) Trials Group
Nov 13, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Mark R MarshallStephen P McDonald
Oct 25, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Konstantinos TsilonisHaralambos Karvounis
Aug 25, 2016·Clinical Journal of the American Society of Nephrology : CJASN·Natalie StaplinJonathan Emberson
Jan 24, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Steven M BrunelliDavid M Spiegel

❮ Previous
Next ❯

Citations

Nov 20, 2019·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Thijs T JanszBrigit C van Jaarsveld
Nov 10, 2020·KI Reports·Bernard CanaudPeter Kotanko
Mar 30, 2021·Kidney International Supplements·Anjay Rastogi, Edgar V Lerma
Jan 21, 2022·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Esra Nagehan Akyol Onder, Pelin Ertan

❮ Previous
Next ❯

Software Mentioned

EURODOPPS
STATA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association
Francess Victoria Nelson DanquahNancy Bergstrom
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Pantelis SarafidisAikaterini Papagianni
Proceedings of the National Academy of Sciences of the United States of America
A SpitL A Casselton
Clinical Kidney Journal
James G HeafHenrik Post Hansen
© 2022 Meta ULC. All rights reserved