The association between maternal psychological stress and inflammatory cytokines in allergic young children

PeerJ
Mayumi TsujiToshihiro Kawamoto

Abstract

Background. Previous studies have shown that psychological stress is linked to asthma prevalence. Parental psychological stress may potentially influence inflammatory responses in their allergic children. The purpose of this study is to clarify the association between maternal psychological status and inflammatory response of allergic young children. Methods. The study subjects were 152 young allergic children (median age: 13 months) who had not shown any allergic symptoms in the past one month. mRNA expression levels of the inflammatory response genes IL-6, IL-8, IL-10 and IL-22 were quantified by qRT-PCR. Maternal psychological status was assessed by standardized questionnaires: the Centre for Epidemiological Studies Depression Scale (CES-D) for depression and the Japanese Perceived Stress Scale (JPSS) for perceived stress. Results. A significant positive association was observed between maternal CES-D scores and IL-6 mRNA expression in the children with asthma. The JPSS scores were also positively associated with IL-8 mRNA expression in asthmatic children and IL-6 mRNA expression in children with allergic rhinitis. Similar trends were observed among children positive for house dust mite-specific IgE, but these associations w...Continue Reading

References

Dec 1, 1983·Journal of Health and Social Behavior·S CohenR Mermelstein
Sep 15, 2004·Progress in Neuro-psychopharmacology & Biological Psychiatry·H M van Praag
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Martine Heyman
Dec 24, 2005·Journal of the American College of Nutrition·Ross G Crittenden, Louise E Bennett
Apr 8, 2009·Brain, Behavior, and Immunity·Andrew J SteelmanC Jane R Welsh
Nov 17, 2009·The Journal of Allergy and Clinical Immunology·Jennifer S LebovidgeLynda C Schneider
Aug 25, 2010·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Jianbo ShiHuabin Li
May 4, 2011·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Valerio FarfarielloGiorgio Santoni
Jan 22, 2013·International Journal of Environmental Research and Public Health·Mayumi TsujiFumio Matsumura
Apr 16, 2013·Current Allergy and Asthma Reports·Vivek D GandhiHarissios Vliagoftis
Nov 19, 2013·World Journal of Gastrointestinal Pathophysiology·Min Kyung JeonNikolaus Gassler
Jan 17, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Amber M PattersonWilliam B Malarkey
Jul 25, 2014·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Sander de KivitAlan L Landay
Oct 9, 2014·Allergy and Asthma Proceedings·Dejan TomljenovicLivije Kalogjera

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Methods Mentioned

BETA
PCR
blood collection

Software Mentioned

STATA
OLIGO

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