The association between mean platelet volume and cardiovascular risk factors

European Journal of Internal Medicine
Nakarin SansanayudhAmmarin Thakkinstian

Abstract

Mean platelet volume (MPV) correlates with platelet activation and has recently emerged as a potential marker of cardiovascular diseases. Previous publications also suggest possible association between MPV and some cardiovascular risk factors but the evidences are still conflicting and inconclusive. To study the association between MPV and cardiovascular risk factors. This is a cross-sectional study using data from the second survey of the Electricity Generating Authority of Thailand (EGAT) cohort. All participants of the survey who had results of MPV were included. Exclusion criteria included subjects with known hematologic disease or subjects with hematocrit <30% or platelet count <140,000/mm(3). The details of cardiovascular risk factors were documented and the association between MPV and risk factors was analyzed using fractional polynomial regression analysis. There were 2727 subjects with MPV results. After excluding those who had hematologic disease, 2642 subjects were included for analysis. Univariate analysis revealed that gender, diabetes, serum triglyceride, hypertension, and prehypertension were associated with MPV. Hematocrit, platelet count and fasting plasma glucose were inversely correlated with MPV. After adjus...Continue Reading

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Citations

Apr 14, 2016·European Journal of Internal Medicine·Chams B MalufPedro G Vidigal
May 14, 2016·European Journal of Internal Medicine·Nakarin Sansanayudh, Ammarin Thakkinstian
Feb 9, 2016·European Journal of Internal Medicine·Cengiz Beyan, Esin Beyan
Nov 5, 2016·Platelets·Patrizia NorisCarlo L Balduini
Jul 10, 2018·Platelets·Marco RanucciEkaterina Baryshnikova
Jul 22, 2018·The Korean Journal of Internal Medicine·AJin ChoJung-Woo Noh
Jun 2, 2018·Journal of Diabetes Research·Zhongwei ZhouHuixiang Ju
Apr 2, 2020·World Journal of Pediatrics : WJP·Shu WuJun-Bao Du
Jun 15, 2021·Clinical and Experimental Hypertension : CHE·Şeref AlpsoyAydın Akyüz
Oct 30, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Faruk Aydınyılmazİbrahim Halil Tanboğa

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