The association between population-based treatment guidelines and adjuvant therapy for node-negative breast cancer. British Columbia/Ontario Working Group

British Journal of Cancer
C SawkaT G Hislop

Abstract

This study evaluated the impact of province-wide treatment guidelines on consistency of adjuvant therapy for node-negative breast cancer. A retrospective population-based cohort study was conducted in the Canadian provinces of British Columbia, which has province-wide guidelines, and Ontario, which does not. All eligible 1991 incident cases of node-negative breast cancer in British Columbia (n = 942) and a similar number of randomly selected 1991 incident cases in Ontario (n = 938) were reviewed. Consistency of adjuvant therapy received was evaluated by stratifying cases into discrete diagnostic groups using several grouping systems, and by then comparing the distribution of treatments received within each diagnostic group in the two provinces. Recursive partitioning was also performed. We observed that patterns of pathology reporting were consistent with awareness of the factors used in the British Columbia guidelines to define indications for adjuvant therapy. Consistency of care was greater in British Columbia than in Ontario by all diagnostic grouping systems and by recursive partitioning (P < 0.001), and the observed patterns in British Columbia corresponded to the British Columbia guidelines. We conclude that population-b...Continue Reading

Citations

Jun 6, 2002·Journal of the National Cancer Institute·Jennifer L MalinPatricia A Ganz
Nov 8, 2003·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Boris KraljFredrick D Ashbury
Apr 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ivo A OlivottoKaren A Gelmon
Jul 1, 2005·Journal of Oncology Practice·Thomas R Barr
May 20, 2003·The Breast Journal·T Gregory HislopCaroline Speers
Dec 7, 2006·International Journal of Cancer. Journal International Du Cancer·Andrew ColdmanLisa Kan
Nov 1, 2008·Medical Oncology·Kenji HayashibaraShigemi Ishikawa
May 14, 1999·Plastic and Reconstructive Surgery·C L TangE Holowaty
May 1, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen K ChiaIvo A Olivotto
May 20, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N Hébert-CroteauL Deschênes
Mar 29, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L WeirI A Olivotto
Nov 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer L MalinRobert H Brook
Oct 13, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H F KenneckeK A Gelmon

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