Aug 1, 1976

The association between serum triglycerides and gamma glutamyl transpeptidase activity in diabetes mellitus

Clinical Biochemistry
J V MartinD M Goldberg

Abstract

A study conducted on 228 diabetic patients has shown a significant positive association between serum gamma-glutamyl transpeptidase (GGT) and triglyceride levels. Both fall with treatment, the most marked reduction occurring in patients on insulin. We suggest that the association between serum GGT and triglyceride levels and also the higher incidence of raised GGT and triglyceride levels in new diabetics may reflect hepatic microsomal enzyme induction of the rate-limiting enzymes of triglyceride synthesis. Serum GGT does not seem to correlate with hepatomegaly in diabetes mellitus.

Mentioned in this Paper

Enzymes, antithrombotic
Gamma-glutamyl transferase
Hepatic
Nodular Glomerulosclerosis
Enzymes for Treatment of Wounds and Ulcers
Enzyme Induction
Diabetic Retinopathy
Hepatomegaly
Enzymes, hematological
Triglyceride Biosynthetic Process

About this Paper

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