The association between visceral adiposity with systemic inflammation, oxidative stress, and risk of post-surgical adhesion

Archives of Physiology and Biochemistry
Mohammad-Hassan Arjmand

Abstract

Abdominal and pelvic adhesions are common post-operative complications. Despite new medical technologies, these adhesions are appearing to be unavoidable and little is known about their causation; for example, why certain patients/or tissues are more prone to adhesions. There have been no clinical studies about increasing the risk adhesions in obese patients, but there is some evidence about the molecular mechanisms involving visceral fat (VF) that may lead to profibrotic conditions. VF is an endocrine/inflammatory organ which produces many biologically active molecules such as adipokines and inflammatory cytokines. Inflammatory conditions, oxidative stress, and the expression some fibrotic molecules in the VF may induce pathological conditions in the abdominal cavity that predispose to the formation of fibrotic bands.

References

Feb 1, 1982·The Journal of Clinical Endocrinology and Metabolism·A H KissebahP W Adams
Jan 1, 1993·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·K E Rodgers, G S diZerega
Jun 1, 1996·Surgery·L HolmdahlB Risberg
Oct 31, 2000·The Journal of Pathology·H SulaimanS E Herrick
Apr 5, 2001·Fertility and Sterility·N CheginiUNKNOWN Peritoneal Healing and Adhesion MultiUniversity Study Group
Jan 26, 2002·Lancet·C L McTernanS Kumar
Apr 27, 2002·British Journal of Pharmacology·Andreas H WagnerMarkus Hecker
Mar 14, 2003·Obesity Research·Rubén NogueirasCarlos Diéguez
May 21, 2003·Proceedings of the National Academy of Sciences of the United States of America·Peter Sartipy, David J Loskutoff
Jan 6, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·J S Yudkin
Jan 29, 2005·American Journal of Respiratory Cell and Molecular Biology·Keira L WattsMonica A Spiteri
Feb 16, 2005·Circulation·Muredach P ReillyDaniel J Rader
Apr 12, 2005·Annual Review of Pharmacology and Toxicology·Max Lafontan
Apr 22, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Maria BokarewaAndrej Tarkowski
Aug 17, 2005·Journal of Thrombosis and Haemostasis : JTH·D E Vaughan
Aug 1, 2006·Thorax·E HothersallN C Thomson
Oct 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Koichi FujitaMichio Shimabukuro

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Citations

Jun 17, 2020·Archives of Physiology and Biochemistry·Gordon A FernsMohammad-Hassan Arjmand
Feb 20, 2021·Journal of Cancer Research and Clinical Oncology·Wenting PeiJizhun Zhang
Aug 28, 2021·Biomedicines·Ali Fatehi HassanabadPaul W M Fedak

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