The association of air pollution with congenital anomalies: An exploratory study in the northern Netherlands

International Journal of Hygiene and Environmental Health
N SalavatiMarian K Bakker

Abstract

There are a growing number of reports on the association between air pollution and the risk of congenital anomalies. However, the results are inconsistent and most studies have only focused on the association of air pollution with congenital heart defects and orofacial clefts. Using an exploratory study design, we aimed to identify congenital anomalies that may be sensitive to maternal exposure to specific air pollutants during the periconceptional period. We conducted a case-control study of 7426 subjects born in the 15 years between 1999 and 2014 and registered in the European Registration of Congenital Anomalies and Twins Northern Netherlands (EUROCAT NNL). Concentrations of various air pollutants (PM10, PM2.5, PM10-2.5, NO2, NOX, absorbance) were obtained using land use regression models from the European Study of Cohorts for Air Pollution Effects (ESCAPE). We linked these data to every subject in the EUROCAT NNL registry via their full postal code. Cases were classified as children or fetuses born in the 15-year period with a major congenital anomaly that was not associated with a known monogenic or chromosomal anomaly. Cases were divided into anomaly subgroups and compared with two different control groups: control group ...Continue Reading

References

Apr 18, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y LinhartM Mazor
Aug 18, 2001·BMJ : British Medical Journal·P ElliottL Jarup
Dec 11, 2002·Proceedings of the National Academy of Sciences of the United States of America·Christopher M SomersJames S Quinn
Aug 11, 2009·Current Opinion in Pediatrics·Andrea Baccarelli, Valentina Bollati
Mar 27, 2010·Cell Biology and Toxicology·Flavia Mazzoli-RochaWalter Araújo Zin
Dec 7, 2010·Environmental Health Perspectives·Martine VrijheidMark Nieuwenhuijsen
Feb 3, 2011·Occupational and Environmental Medicine·Marloes EeftensGerard Hoek
Feb 19, 2011·Environmental Research·Payam DadvandTanja Pless-Mulloli
Apr 30, 2013·Environmental Research·Keren Agay-ShayChava Peretz
Oct 11, 2013·Birth Defects Research. Part A, Clinical and Molecular Teratology·Amy M PadulaGary M Shaw
Jan 2, 2014·Environmental Health Perspectives·Anna SchembariMartine Vrijheid
Jan 17, 2014·The Lancet. Respiratory Medicine·Marie PedersenRémy Slama
Aug 5, 2014·International Journal of Environmental Research and Public Health·Esther Kai-Chieh ChenSéverine Deguen

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Citations

Sep 19, 2020·Cost Effectiveness and Resource Allocation : C/E·Ying LiYung-Ho Chiu
Aug 17, 2020·International Journal of Environmental Research and Public Health·Cezary WojtylaGrzegorz Panek
Nov 30, 2020·The Science of the Total Environment·Qi ZhangJiyu Cao
Jan 31, 2020·Environmental Research·Ching-Chun HuangYue Leon Guo
Apr 18, 2021·Environmental Geochemistry and Health·Shu SunJiyu Cao
Jul 12, 2021·Annals of the New York Academy of Sciences·Shuang ZhangQi-Jun Wu
Sep 8, 2021·Environmental Science and Pollution Research International·Guangxia YuHuangyuan Li

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