The association of baseline left atrial structure and function measured with cardiac magnetic resonance and pulmonary vein isolation outcome in patients with drug-refractory atrial fibrillation

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Mohammadali HabibiSaman Nazarian

Abstract

Prognostic significance of left atrial (LA) function in patients with atrial fibrillation (AF) is poorly defined. To examine the association of LA function measured with cardiac magnetic resonance (CMR) feature-tracking and AF recurrence following catheter ablation. One hundred and twenty-one AF patients (72% paroxysmal, mean age 59 ± 10 years) were enrolled. Baseline LA function was measured by calculating passive, active, and total emptying fractions (LAEF) and analysis of global longitudinal strain and strain rates. Patients were followed up for recurrence of AF or atrial tachycardia (AT). Hazard ratios for recurrence were calculated using Cox proportional models adjusted for potential clinical confounders, type of AF, left ventricular ejection fraction, AF duration, LA volume, and late gadolinium enhancement (LGE). During a mean follow-up of 18 ± 9 months, 52 patients (43%) experienced recurrent AF/AT. Patients with recurrent AF/AT had higher baseline LA volume index and lower LA passive, and total LAEF (P < .05 for all). The baseline peak LA strain and strain rates in all phases of LA function were lower in the AF/AT recurrence group (P < .01 for all). In multivariable analysis total LAEF, peak LA strain, and systolic and ...Continue Reading

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Citations

Aug 30, 2016·Journal of Cardiovascular Electrophysiology·Mayank SardanaDavid D McManus
Mar 8, 2017·Expert Review of Cardiovascular Therapy·Louisa O'NeillSteven E Williams
Oct 13, 2016·Circulation. Cardiovascular Imaging·Flemming Javier OlsenTor Biering-Sørensen
Dec 7, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Esra Gucuk IpekSaman Nazarian
Jul 4, 2018·Arrhythmia & Electrophysiology Review·Rahul K MukherjeeMark D O'Neill
Dec 14, 2017·European Heart Journal Cardiovascular Imaging·S LiddyO Buckley
Jan 2, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jo-Nan LiaoShih-Ann Chen
May 27, 2020·Cardiac Electrophysiology Clinics·Mohammadali HabibiHugh Calkins
Oct 18, 2020·Trends in Cardiovascular Medicine·Valentina MangiaficoSyed Ahsan

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