PMID: 11927967Apr 3, 2002Paper

The association of benign and malignant ovarian adenofibromas with breast cancer and thyroid disorders

International Journal of Surgical Pathology
Elvio G SilvaDavid M Gershenson

Abstract

An unexpected association with breast cancer and thyroid disorders was found during a review of 91 cases of benign and malignant ovarian adenofibromas. Sixty-three tumors were benign, 11 had areas of borderline neoplasms, and 17 had a component of carcinoma. Such tumors were divided into glandular/cystic (61 cases) and papillary (30 cases) according to their gross and microscopic appearance. Among the 61 patients with glandular/cystic adenofibromas, 13 (21%) had breast cancer and 19 (31%) also had thyroid disorders. Among the 30 patients with papillary adenofibromas there were no cases of breast cancer and only 2 patients had thyroid disorders. The average age of the patients with ovarian adenofibroma and breast cancer or thyroid disorders was higher (66 years) than that of patients without breast cancer or thyroid disorders (55 years). More patients with breast cancer and thyroid disorders had bilateral adenofibromas than patients without breast cancer or thyroid disorders. We also reviewed the medical records of 100 patients with ovarian cancer without adenofibroma component, 100 patients with breast cancer, and 100 patients with ovarian and breast cancer. Six percent of patients with ovarian cancer had breast cancer and 16% ...Continue Reading

References

Dec 1, 1978·The American Journal of Surgical Pathology·G F Kao, H J Norris
Feb 15, 1975·American Journal of Obstetrics and Gynecology·L Papadaki, J O Beilby
Jan 1, 1991·Archives of Gynecology and Obstetrics·D H MooreP J Santrach
Mar 1, 1991·The American Journal of Surgical Pathology·D A Bell
Jan 1, 1990·Epidemiologic Reviews·M B Goldman
Mar 1, 1985·The American Journal of Surgical Pathology·D A Bell, R E Scully
Jan 1, 1974·Cancer·R D JensenJ F Fraumeni
Sep 1, 1967·American Journal of Obstetrics and Gynecology·G Hermann
Sep 1, 1967·American Journal of Obstetrics and Gynecology·S A Wolfe, D L Seckinger
Dec 1, 1984·British Journal of Obstetrics and Gynaecology·P HiltonA Watson
Feb 3, 1984·JAMA : the Journal of the American Medical Association·D A HoffmanJ F Fraumeni
Apr 1, 1994·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A GroutzM P David
Dec 1, 1993·Histopathology·E MannionA I al-Nafussi
Jun 1, 1997·Annals of Medicine·P P Smyth
Jun 19, 1998·The Journal of Obstetrics and Gynaecology Research·K UshijimaM Yakushiji
Feb 19, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H F VasenM Caligo
Mar 26, 1999·Cancer·R Vassilopoulou-SellinC S Cooksley
Jan 21, 2000·Genetic Epidemiology·A C AntoniouD F Easton
Jun 1, 1959·American Journal of Obstetrics and Gynecology·J R McNULTY
Jun 1, 1950·The Journal of Obstetrics and Gynaecology of the British Empire·D DALEYW G MILLAR

❮ Previous
Next ❯

Citations

Sep 16, 2003·Cancer·Elisabeth AdjadjFlorent de Vathaire
Apr 9, 2014·The Journal of Clinical Endocrinology and Metabolism·Yiyi ZhangEliseo Guallar
Mar 18, 2019·Advances in Therapy·Qiong YangKefeng Lei

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.