The association of dysglycaemia and cardiovascular disease in patients with metabolic syndrome

The Journal of International Medical Research
W GongRenming Hu

Abstract

The objective of this study was to investigate the relationship between increased prevalence of cardiovascular disease and glucose regulation status in Chinese patients with metabolic syndrome (MetS). All patients underwent an oral glucose tolerance test (2-h post-load plasma glucose) to determine their glucose regulation status and had their brachial-ankle pulse wave velocity (baPWV) measured. Of the 590 patients included in the study, 115 (19.5%) had normal glucose tolerance, 114 (19.3%) had impaired fasting glucose (IFG) alone, 38 (6.4%) had impaired glucose tolerance (IGT) alone, 197 (33.4%) had diabetes mellitus and 126 (21.4%) had combined glucose intolerance (CGI; IFG plus IGT). Patients with diabetes mellitus had a significantly higher baPWV compared with all other groups and patients with CGI had a significantly higher baPWW compared with patients with IFG. Dysglycaemia was common in patients with MetS. An increased prevalence of cardiovascular disease in patients with MetS was related to their glucose regulation status.

References

Apr 1, 1992·Diabetes Care·E FerranniniS M Haffner
Jul 24, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tadahiro KuboChuwa Tei
Jul 24, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Akira YamashinaYoshio Yamamoto
Oct 28, 2003·Diabetes Care·Saul GenuthUNKNOWN Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
Nov 25, 2003·Diabetes Care·UNKNOWN American Diabetes Association
Aug 11, 2005·The Journal of Clinical Endocrinology and Metabolism·Christoph H SaelyHeinz Drexel
Sep 27, 2005·Lancet·K George M M AlbertiUNKNOWN IDF Epidemiology Task Force Consensus Group
Dec 16, 2005·The American Journal of the Medical Sciences·Kristi Reynolds, Jiang He
Feb 17, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Rita Kohen AvramogluKhosrow Adeli
Jul 2, 2008·Diabetes Care·Earl S FordNaveed Sattar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.