The Association of H1N1 Pandemic Influenza with Congenital Anomaly Prevalence in Europe: An Ecological Time Series Study

Epidemiology
Johannes Michiel LuteijnHelen Dolk

Abstract

In the context of the European Surveillance of Congenital Anomalies (EUROCAT) surveillance response to the 2009 influenza pandemic, we sought to establish whether there was a detectable increase of congenital anomaly prevalence among pregnancies exposed to influenza seasons in general, and whether any increase was greater during the 2009 pandemic than during other seasons. We performed an ecologic time series analysis based on 26,967 pregnancies with nonchromosomal congenital anomaly conceived from January 2007 to March 2011, reported by 15 EUROCAT registries. Analysis was performed for EUROCAT-defined anomaly subgroups, divided by whether there was a prior hypothesis of association with influenza. Influenza season exposure was based on World Health Organization data. Prevalence rate ratios were calculated comparing pregnancies exposed to influenza season during the congenital anomaly-specific critical period for embryo-fetal development to nonexposed pregnancies. There was no evidence for an increased overall prevalence of congenital anomalies among pregnancies exposed to influenza season. We detected an increased prevalence of ventricular septal defect and tricuspid atresia and stenosis during pandemic influenza season 2009, ...Continue Reading

References

Jan 1, 1990·Epidemiology·K J Rothman
Dec 16, 1998·American Journal of Epidemiology·K M NeuzilM R Griffin
Jun 26, 1999·Respirology : Official Journal of the Asian Pacific Society of Respirology·N S WangF F Chen
Nov 6, 2001·Journal of Medical Genetics·J Amiel, S Lyonnet
Jul 27, 2002·Circulation Research·Wouter H Lamers, Antoon F M Moorman
Aug 26, 2006·Birth Defects Research. Part A, Clinical and Molecular Teratology·Marshall J Edwards
Dec 25, 2007·The Lancet Infectious Diseases·Tippi K MakDina Pfeifer
Jan 9, 2008·Birth Defects Research. Part A, Clinical and Molecular Teratology·Andrew E CzeizelFerenc Bánhidy
Aug 1, 2009·Lancet·Denise J JamiesonUNKNOWN Novel Influenza A (H1N1) Pregnancy Working Group
Oct 13, 2009·Occupational and Environmental Medicine·H DolkD Wellesley
Dec 25, 2009·The New England Journal of Medicine·Janice K LouieUNKNOWN California Pandemic (H1N1) Working Group
Jan 27, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Saliya HewagamaMichelle L Giles
Mar 24, 2010·Obstetrics and Gynecology·Andreea A CreangaMargaret A Honein
Apr 22, 2010·JAMA : the Journal of the American Medical Association·Alicia M SistonUNKNOWN Pandemic H1N1 Influenza in Pregnancy Working Group
Sep 3, 2010·Pediatric Surgery International·Polina FrolovMichael D Klein
Nov 23, 2010·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·J MereckieneUNKNOWN VENICE project gatekeepers group
Jan 25, 2011·The Journal of Pediatrics·Matthew E OsterAdolfo Correa
Mar 9, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Maria LoaneUNKNOWN EUROCAT Working Group
Mar 9, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Patricia A BoydHelen Dolk
Oct 22, 2011·BMC Public Health·Johannes M LuteijnGordon J Marnoch
Feb 3, 2012·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·J MereckieneUNKNOWN VENICE project gatekeepers group
Jul 12, 2012·JAMA : the Journal of the American Medical Association·Björn PasternakAnders Hviid
Jun 14, 2013·International Journal of Epidemiology·Krishnan BhaskaranBen Armstrong
Dec 25, 2013·Human Reproduction·J M LuteijnH Dolk
Mar 19, 2014·Birth Defects Research. Part A, Clinical and Molecular Teratology·Johannes Michiel LuteijnLyubov Yevtushok

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Citations

Jul 28, 2016·American Journal of Epidemiology·Deshayne B FellKumanan Wilson
Feb 27, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ying ZhouBin Yu

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