The association of infrared imaging findings of the breast with prognosis in breast cancer patients: an observational cohort study

BMC Cancer
Li-An WuJane Wang


To evaluate whether infrared (IR) imaging findings are associated with prognosis in patients with invasive breast carcinomas. This study was approved by the institutional review board of the research ethics committee of our hospital, and all participants gave written informed consent. From March 2005 to June 2007, we enrolled 143 patients with invasive breast cancer that underwent preoperative IR imaging. We used five IR signs to interpret breast IR imaging. Cox proportional hazards model was used to evaluate the effect of IR signs on long-term mortality. During a median follow-up of 2451 days (6.7 years), 31 patients died. Based on the Cox Proportional Hazards Model, IR1 sign (the temperature of cancer site minus that of the contralateral mirror imaging site) was positively associated with mortality in the univariate analysis (overall mortality hazard ratio [HR], 2.29; p = 0.03; disease-specific mortality HR, 2.57; p = 0.04) as well as the multivariate analysis after controlling for clinicopathological factors (overall mortality HR, 3.85; p = 0.01; disease-specific mortality HR, 3.91, p = 0.02). In patients with clinical stage I and II disease, IR1 was also positively associated with mortality (overall mortality HR, 3.76; p = ...Continue Reading

Associated Clinical Trials


Jul 29, 1976·The New England Journal of Medicine·M MoskowitzD Mandel
Jan 1, 1980·Annals of the New York Academy of Sciences·M Gautherie
Jul 15, 1982·Cancer·E E SternsJ R Hancock
Nov 30, 1993·Annals of the New York Academy of Sciences·J F HeadR L Elliott
Sep 11, 2002·Breast Cancer Research and Treatment·Shozo OhsumiHisashi Usuki
Dec 20, 2002·AJR. American Journal of Roentgenology·Y R PariskyK Callahan
Mar 5, 2003·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Jonathan F Head, Robert L Elliott
Jan 9, 2010·Biomedical Engineering Online·Jane WangTiffany Ting-Fang Shih

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Apr 24, 2019·Journal of Medical Systems·R Ramya Devi, G S Anandhamala

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