The association of lifetime physical inactivity with bladder and renal cancer risk: A hospital-based case-control analysis

Cancer Epidemiology
Rikki CanniotoKirsten B Moysich

Abstract

Recreational physical inactivity has been gaining recognition as an independent epidemiological exposure of interest in relation to cancer endpoints due to evidence suggesting that it may associate with cancer independent of obesity. In the current analyses, we examined the associations of lifetime recreational physical inactivity with renal and bladder cancer risk. In this hospital-based case-control study, we identified N=160 renal cancer patients, N=208 bladder cancer patients, and N=766 age frequency-matched controls without cancer. Participants self-reporting never participating in any regular/weekly recreational physical activity throughout their lifetime were classified as physically inactive. Utilizing unconditional multivariable logistic regression analyses, we estimated odds ratios and 95% confidence intervals to represent the associations between lifetime physical inactivity and renal and bladder cancer risk. In multivariable logistic regression models, we observed significant positive associations between lifetime recreational physical inactivity and renal cancer and bladder cancer risk: odds ratio=1.77 (95% CI: 1.10-2.85) and odds ratio=1.73 (95% CI: 1.13-2.63), respectively. Similar associations also persisted amo...Continue Reading

Citations

Jun 2, 2020·Head & Neck·Jacob FriedKirsten B Moysich
May 12, 2020·International Journal of Cancer. Journal International Du Cancer·Yueyao LiJuhua Luo
Jun 12, 2020·Journal of Gastrointestinal Cancer·Megha PratapwarKirsten B Moysich

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