The Association of Perceived Memory Loss with Osteoarthritis and Related Joint Pain in a Large Appalachian Population

Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Kim E Innes, Usha Sambamoorthi

Abstract

Previous studies have documented memory impairment in several chronic pain syndromes. However, the potential link between memory loss and osteoarthritis (OA), the second most common cause of chronic pain, remains little explored. In this cross-sectional study, we examine the association of perceived memory loss to OA and assess the potential mediating influence of sleep and mood disturbance in a large Appalachian population. Cross-sectional. US Ohio Valley. A total of 21,982 Appalachian adults age 40 years or older drawn from the C8 Health Project (N = 19,004 adults without and 2,478 adults with OA). All participants completed a comprehensive health survey between 2005 and 2006. Medical history, including physician diagnosis of OA, lifestyle factors, short- and long-term memory loss, sleep quality, and mood were assessed via self-report. After adjustment for demographic, lifestyle, health-related, and other factors, participants with OA were almost three times as likely to report frequent memory loss (adjusted odds ratios [ORs] for short- and long-term memory loss, respectively = 2.7, 95% confidence interval [CI] = 2.2-3.3, and 2.6, 95% CI = 2.0-3.3). The magnitude of these associations increased significantly with rising frequ...Continue Reading

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Citations

Nov 30, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Mustapha Zeddou
Jan 7, 2021·Tissue Engineering. Part C, Methods·Meagan J MakarczykHang Lin
Jan 21, 2021·Journal of Orthopaedic Surgery and Research·Simin LuoQiping Shi
Dec 29, 2020·Frontiers in Aging Neuroscience·Robert A Culibrk, Mariah S Hahn

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