The association of quantitative EEG and MRI in Creutzfeldt-Jakob Disease

Acta Neurologica Scandinavica
S AppelI Blatt

Abstract

Previous studies showed concordance between the typical Periodic Sharp Wave Complex (PSWC) activity in EEG of Creutzfeldt-Jakob Disease (CJD) patients and the MRI findings, while the concordance with slow activity in EEG is less established. The aim of this study was to better characterize the association between MRI findings and EEG changes using quantitative EEG (qEEG) analysis. The demographics, clinical features, and the MRI findings of 12 familial E200K patients with CJD were gathered. EEG test was done and reviewed for the typical PSWC and for the non-specific slow activity. A possible association between the MRI findings and the EEG activity was examined. Then, EEG was analyzed using qEEG tool, and the association between the qEEG finding and the MRI was examined. Twelve patients were included in the study (67% women). Cortical MRI lesions finding were seen in 6/12 (50%) of the patients, and deep gray mater lesions were seen in 8/12 patients (67%). EEG showed the classic PSWC in 6/12 (50%) of the patients where slow activity was seen in 10/12 (83%). Slow activity and cortical MRI findings were associated in only 2/6 (33%) where deep gray matter findings and the slow activity had concordance of 4/8 (50%). qEEG analysis im...Continue Reading

References

Sep 1, 1991·European Journal of Epidemiology·A D Korczyn
Apr 18, 1991·The New England Journal of Medicine·K HsiaoR Gabizon
Sep 2, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Denise M CambierAllen J Aksamit
Feb 24, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·R S G Knight, R G Will
Jul 23, 2005·Annals of Neurology·Constanze BoesenbergInga Zerr
Sep 24, 2009·Brain : a Journal of Neurology·I ZerrP Sanchez-Juan
Oct 16, 2009·Journal of the Neurological Sciences·Ilana SerorIsak Prohovnik
Feb 2, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S A AppelO S Cohen
Aug 13, 2011·Journal of Neurology·Shmuel A AppelIlan Blatt
May 12, 2012·AJNR. American Journal of Neuroradiology·H LeeI Prohovnik
Mar 7, 2014·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Federico CaobelliUgo Paolo Guerra
Nov 5, 2014·Brain : a Journal of Neurology·Eduardo CaverzasiRoland G Henry
Jul 15, 2016·Journal of Neurology, Neurosurgery, and Psychiatry·Edit FrankoSimon Mead
Sep 15, 2016·Journal of Neural Transmission·Oren S CohenChen Hoffmann
Oct 7, 2018·Neurology·Victor J GeraedtsMaria Fiorella Contarino
May 17, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Jeffrey D LewineLindell Weaver

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

Bovine Spongiform Encephalopathy (MDS)

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

Related Papers

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
M B Sundaram, G B Young
The Journal of Infection
M J Painter
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Ehtesham HaiderMuhammad Tariq
© 2021 Meta ULC. All rights reserved