The Association of Recreational and Competitive Running With Hip and Knee Osteoarthritis: A Systematic Review and Meta-analysis

The Journal of Orthopaedic and Sports Physical Therapy
Eduard Alentorn-GeliJón Karlsson

Abstract

Study Design Systematic review and meta-analysis. Background Running is a healthy and popular activity worldwide, but data regarding its association with osteoarthritis (OA) are conflicting. Objectives To evaluate the association of hip and knee OA with running and to explore the influence of running intensity on this association. Methods PubMed, Embase, and Cochrane Library databases were used to identify studies investigating the occurrence of OA of the hip and/or knee among runners. A meta-analysis of studies comparing this occurrence between runners and controls (sedentary, nonrunning individuals) was conducted. Runners were regarded as "competitive" if they were reported as professional/elite athletes or participated in international competitions. Recreational runners were individuals running in a nonprofessional (amateur) context. The prevalence rate and odds ratio (with 95% confidence interval [CI]) for OA between runners (at competitive and recreational levels) and controls were calculated. Subgroup analyses were conducted for OA location (hip or knee), sex, and years of exposure to running (less or more than 15 years). Results Twenty-five studies (n = 125810 individuals) were included and 17 (n = 114829 individuals) we...Continue Reading

References

May 24, 1975·British Medical Journal·J PuranenJ Saarela
Jul 1, 1990·The American Journal of Sports Medicine·L KonradsenL Søndergaard
Jun 1, 1983·British Journal of Sports Medicine·M McDermott, P Freyne
Jan 1, 1995·Journal of Clinical Epidemiology·G GrégoireJ Le Lorier
May 1, 1994·Annals of Epidemiology·R L ImeokpariaS M Marlowe
Jan 22, 1994·BMJ : British Medical Journal·U M KujalaS Sarna
Mar 1, 1994·The American Journal of Sports Medicine·H RoosH Wingstrand
Mar 1, 1993·The American Journal of Sports Medicine·E VingårdC Hogstedt
Apr 1, 1993·Acta Orthopaedica Scandinavica·H LindbergP Gärdsell
Feb 17, 1997·The Medical Journal of Australia·A DeaconP Brukner
Feb 25, 1998·The American Journal of Sports Medicine·E VingårdH Malchau
Feb 24, 1999·European Journal of Applied Physiology and Occupational Physiology·J A KettunenS Sarna
Jul 23, 1999·Medicine and Science in Sports and Exercise·U M KujalaJ Karjalainen
Feb 24, 2001·The American Journal of Sports Medicine·J A KettunenS Sarna
Feb 14, 2002·Osteoarthritis and Cartilage·E LucchinettiP A Torzilli
Sep 29, 2004·Osteoarthritis and Cartilage·Laurent GaloisPierre Gillet
Sep 19, 2006·Scandinavian Journal of Medicine & Science in Sports·N ThelinA Thelin
Sep 1, 2007·The American Journal of Sports Medicine·L Stefan LohmanderEwa M Roos
Jun 14, 2008·American Journal of Preventive Medicine·Eliza F ChakravartyJames F Fries
Feb 1, 1995·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·R S PanushR Thoburn
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Nov 19, 2009·International Archives of Occupational and Environmental Health·Ilias VrezasAndreas Seidler
Jul 9, 2010·Clinics in Sports Medicine·Stuart E Willick, Pamela A Hansen
Apr 18, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Jeffrey BeckettZijun Zhang
Feb 5, 2013·Medicine and Science in Sports and Exercise·Paul T Williams
May 23, 2015·Clinical Orthopaedics and Related Research·Alex N BastickSita M A Bierma-Zeinstra
Jul 17, 2015·Sports Medicine·Luiz Carlos Hespanhol JuniorEvert Verhagen
Apr 23, 2016·Annals of Physical and Rehabilitation Medicine·Marie-Martine Lefèvre-ColauAlexandra Roren
Jul 31, 2016·The American Journal of Sports Medicine·Jonathan M VigdorchikJohn C Clohisy
Aug 16, 2016·The American Journal of Sports Medicine·Kate A TimminsKimberley L Edwards

❮ Previous
Next ❯

Citations

Apr 20, 2018·The Journal of Orthopaedic and Sports Physical Therapy·Søren T SkouChristian Barton
Nov 23, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Theresa DiermeierAndrea Achtnich
Jan 18, 2018·The Journal of Bone and Joint Surgery. American Volume·Gwo-Chin Lee
Apr 20, 2019·American Journal of Physical Medicine & Rehabilitation·Brenda CastilloWilliam Micheo
Dec 12, 2017·Current Opinion in Rheumatology·Ernest R Vina, C Kent Kwoh
Aug 7, 2019·Current Sports Medicine Reports·Trevor Gessel, Mark A Harrast
May 2, 2018·International Journal of Environmental Research and Public Health·Karen L TroyJoshua E Johnson
Jul 20, 2019·JMIR Medical Informatics·Bo ShengYanxin Zhang
Jan 3, 2019·Sports Medicine and Arthroscopy Review·Richard W Willy, Max R Paquette
Apr 5, 2018·The Medical Journal of Australia·John W Orchard
Jan 23, 2021·Exercise and Sport Sciences Reviews·Inger MechlenburgUlrik Dalgas
Jun 3, 2021·Journal of Orthopaedic Surgery and Research·Ni ZengGuo-Xin Ni
Jul 3, 2021·Journal of Sports Science & Medicine·Dennie van den NoortVincent Gouttebarge
Jun 17, 2021·Clinics·Nathalie Ferrari Bechara AndereJúlia Maria D'Andréa Greve
Sep 4, 2021·Sports Medicine·Michaela C M KhanJean-Francois Esculier
Sep 21, 2021·Sports Medicine·Volker ScheerDaniel Rojas-Valverde
Oct 2, 2021·The Journal of Orthopaedic and Sports Physical Therapy·Jay-Shian TanPeter Kent

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.