The association of triglyceride and glucose index, and triglyceride to high-density lipoprotein cholesterol ratio with prehypertension and hypertension in normoglycemic subjects: A large cross-sectional population study.

The Journal of Clinical Hypertension
fomin zhangHongliang Cong

Abstract

Insulin resistance (IR) plays an important role in the development of hypertension. Triglyceride and glucose index (TyG index), and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-c) as effective IR surrogate indexes have been verified in numerous studies. Therefore, the authors conducted a large cross-sectional study to explore the association of TyG index and TG/HDL-c with prehypertension and hypertension in the same normoglycemic subjects from Tianjin, China. A total of 32 124 adults were eligible for this study. According to the level of blood pressure, the enrolled individuals were divided into three groups, which were normotension, prehypertension, and hypertension. In multiple logistic regression analysis, there was associated with prehypertension and hypertension when comparing the highest TyG index to the lowest TyG index and corresponding ORs were 1.795 (1.638, 1.968) and 2.439 (2.205, 2.698), respectively. For TG/HDL-c, the corresponding ORs were 1.514 (1.382, 1.658) and 1.934 (1.751, 2.137), respectively. Furthermore, when comparing the fourth quartile to the first quartile of TyG index and TG/HDL-c, respectively, both corresponding ORs of hypertension were higher than prehypertension. Elevated Ty...Continue Reading

References

Sep 1, 1979·The American Journal of Physiology·R A DeFronzoR Andres
Oct 1, 1988·American Journal of Hypertension·R P Ames
Aug 1, 1994·European Heart Journal·K RettH Mehnert
Dec 6, 2003·Hypertension·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Mar 28, 2006·The American Journal of Medicine·Theodore W Kurtz
Sep 19, 2006·Best Practice & Research. Clinical Endocrinology & Metabolism·Valéria Lamounier-ZepterStefan R Bornstein
Aug 21, 2007·Lancet·Franz H MesserliEberhard Ritz
Dec 11, 2008·Metabolic Syndrome and Related Disorders·Luis E Simental-MendíaFernando Guerrero-Romero
May 21, 2010·The Journal of Clinical Endocrinology and Metabolism·Fernando Guerrero-RomeroMartha Rodríguez-Morán
Aug 11, 2010·Nature Reviews. Cardiology·Guido LastraJames R Sowers
Aug 13, 2013·Metabolism: Clinical and Experimental·Annayya R AroorJames R Sowers
Dec 19, 2015·Nature Reviews. Endocrinology·Guanghong JiaJames R Sowers
Nov 12, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Feng WangDayi Hu
Feb 17, 2018·Circulation·Zengwu WangUNKNOWN China Hypertension Survey Investigators
Mar 21, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Mitsuru Ohishi
Apr 25, 2019·Nature Reviews. Nephrology·John E HallMichael E Hall
Apr 30, 2019·Metabolic Syndrome and Related Disorders·Cornelia BalaMaria Dorobantu
May 14, 2019·European Journal of Pediatrics·Luis E Simental-MendíaFernando Guerrero-Romero
Jun 12, 2019·Diabetes Care·Kahui ParkJong Suk Park
Jun 19, 2019·Metabolic Syndrome and Related Disorders·Jie FanXing Zhen Liu
Aug 7, 2019·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Yanxia XieLiqiang Zheng
Aug 31, 2019·Primary Care Diabetes·Panya ChamroonkiadtikunWorawit Wanichanon
Apr 8, 2020·International Journal of Endocrinology·Adriana Sánchez-GarcíaJosé Gerardo González-González
Jun 13, 2020·Journal of the American College of Cardiology·Chi WangHao Xue
Nov 11, 2020·Metabolic Syndrome and Related Disorders·Taiwo H RaimiOladimeji A Ajayi

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