The availability of HEPA-filtered rooms and the incidence of pneumonia in patients after haematopoietic stem cell transplantation (HSCT): results from a prospective, multicentre, eastern European study

Journal of Clinical Nursing
Samuel VokurkaJana Bocková

Abstract

To establish the availability of High Efficiency Particulate Air (HEPA)- and nonHEPA-filtered rooms in eastern European transplant centres and to investigate the impact on incidence of pneumonia and mortality after haematopoietic stem cell transplantation (HSCT). Barrier nursing in HEPA-filtered rooms is generally recommended for patients undergoing HSCT. There are only limited data on the availability of HEPA-filtered rooms and the impact on incidence of pneumonia and mortality. A prospective, observational, international study. Monitoring cards were distributed within the East Forum EBMT-Nurses Group cooperating centres, and 689 consecutive patients were registered in 1/2010-6/2012. Patients were monitored for 100 days post-transplant. In patients undergoing autologous HSCT, pneumonia developed in 14/400 (3·5%) and was the cause of death in 2/14 (14%) of patients. There was no significant difference in mortality between HEPA-filtered and nonHEPA-filtered groups (4·5% vs. 4·9%, respectively). 239/400 (59%) transplantations were performed in single-bed rooms [190/239 (79%) HEPA-filtered] and 161 (41%) in two-bed rooms [28/161 (17%) HEPA-filtered]. In allogeneic transplantation, pneumonia developed in 24/289 (8·3%) and was the c...Continue Reading

References

Jan 19, 2002·Journal of Hematotherapy & Stem Cell Research·W H KrügerUNKNOWN European group for blood and marrow transplantation
Oct 23, 2008·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Stephanie J LeeSteven Joffe
Oct 29, 2009·Bone Marrow Transplantation·D YokoeUNKNOWN Centers for Disease Control and Prevention

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Citations

Mar 22, 2016·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J-H ErdmannO Penack
Feb 25, 2017·Journal of Clinical Nursing·Valentina BiagioliMaria Grazia De Marinis
Jun 25, 2016·Annals of Hematology·Andrew J UllmannUNKNOWN Infectious Diseases Working Party of the German Society for Hematology and Medical Oncology (AGIHO/DGHO) and the DAG-KBT (Ge

Jan 5, 2021·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Oct 1, 2020·Expert Review of Hematology·Andrea BacigalupoLivio Pagano
Jul 15, 2021·Revista brasileira de enfermagem·Jéssica Alline Pereira RodriguesNayla Tamara de Godoi Caceres

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