The basement membrane complex of the human corneal epithelium

Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
H Brewitt, E Reale

Abstract

The present report reviews the fine structure of the basement membrane zone or complex in the normal human cornea and describes its alterations in cases of early and acute keratoconus. In normal human cornea the basement membrane zone is formed by a basal lamina (with a lamina lucida and a lamina densa), "special fibrils", collagen fibrils and assemblies of filaments. These components are less evident in the central region of the cornea than in its periphery. In early stages of keratoconus the basement membrane zone is thickened and the lamina densa displays an irregular course. In acute keratoconus, the basement membrane zone is also thickened and includes a large number of "special fibrils" as well as bundles of "microfibrils" (oxytalan fibers). The conclusion that the basement membrane complex of the corneal epithelium is equivalent to the epidermal-dermal junction of the skin is discussed.

References

Jun 1, 1975·American Journal of Ophthalmology·J A FogleW R Green
May 1, 1977·American Journal of Ophthalmology·B S FineF D Slaughter
Nov 8, 1978·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·Y PouliquenM Savoldelli
Dec 1, 1978·The British Journal of Ophthalmology·A J Dark
Mar 1, 1977·American Journal of Ophthalmology·J A FogleW J Stark
Jan 1, 1977·Advances in Experimental Medicine and Biology·R RossL K Altman
Apr 1, 1975·Journal of Ultrastructure Research·S K Fisher, K A Linberg
Aug 11, 1975·The Journal of Investigative Dermatology·R A Briggaman, C E Wheeler
Apr 1, 1974·American Journal of Ophthalmology·J A FogleK R Kenyon
Jan 1, 1974·Journal of Oral Pathology·H M FullmerA J Narkates
Mar 1, 1968·American Journal of Ophthalmology·A A KhodadoustJ E Dowling
Aug 1, 1969·The Journal of Cell Biology·R R Bruns
Oct 1, 1965·The Journal of Cell Biology·G E Palade, M G Farquhar
Nov 1, 1958·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H M FULLMER, R D LILLIE
Nov 1, 1960·American Journal of Ophthalmology·J KAYES, A HOLMBERG
May 15, 1965·American Journal of Obstetrics and Gynecology·M S YOUNESS A BENCOSME
Feb 1, 1962·The Anatomical Record·F N LOW

❮ Previous
Next ❯

Citations

May 31, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jessica H MathewJan P G Bergmanson
Oct 1, 1992·The British Journal of Ophthalmology·G E MarshallW R Lee
Aug 1, 1993·The British Journal of Ophthalmology·G E MarshallW R Lee
Jun 1, 1996·The British Journal of Ophthalmology·C A GauthierH Hamberg-Nyström
Jan 1, 1991·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G E MarshallW R Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.