The BaSICS (Baby Skin Integrity Comparison Survey) study: A prospective experimental study using maternal observations to report the effect of baby wipes on the incidence of irritant diaper dermatitis in infants, from birth to eight weeks of age.

Pediatrics and Neonatology
Alan D PriceFiona MacVane Phipps

Abstract

Baby wipes have been shown to be safe and effective in maintaining skin integrity when compared to the use of water alone. However, no previous study has compared different formulations of wipe. The aim of the BaSICS study was to identify any differences in incidence of irritant diaper dermatitis (IDD) in infants assigned to three different brands of wipe, all marketed as suitable for neonates, but which contained varying numbers of ingredients. Women were recruited during the prenatal period. Participants were randomly assigned to receive one of three brands of wipe for use during the first eight weeks following childbirth. All participants received the same nappies. Participants reported their infant's skin integrity on a scale of 1-5 daily using a bespoke smartphone application. Analysis of effect of brand on clinically significant IDD (score 3 or more) incidence was conducted using a negative binomial generalised linear model, controlling for possible confounders at baseline. Analysts were blind to brand of wipe. Of 737 women enrolled, 15 were excluded (admitted to neonatal intensive care, premature or other infant health issues). Of the 722 eligible babies, 698 (97%) remained in the study for the full 8-week duration, 24.6...Continue Reading

References

Apr 1, 1992·Contact Dermatitis·F LonghiP Amerio
Jun 1, 1986·Pediatric Dermatology·W E JordanA M Marrer
Sep 12, 2000·Archives of Pediatrics & Adolescent Medicine·D B WardD P Krowchuk
Oct 26, 2007·Pediatric Dermatology·Shazia AdalatHelen Goodyear
Dec 5, 2012·The Journal of International Medical Research·C H LiY H Dai
Jun 18, 2016·International Journal of Dermatology·David J Atherton

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