The Behavioral and Cognitive Executive Disorders of Stroke: The GREFEX Study

PloS One
M RousselGREFEX study group

Abstract

Many studies have highlighted the high prevalence of executive disorders in stroke. However, major uncertainties remain due to use of variable and non-validated methods. The objectives of this study were: 1) to characterize the executive disorder profile in stroke using a standardized battery, validated diagnosis criteria of executive disorders and validated framework for the interpretation of neuropsychological data and 2) examine the sensitivity of the harmonization standards protocol proposed by the National Institute of Neurological Disorders and Stroke and Canadian Stroke Network (NINDS-CSN) for the diagnosis of Vascular Cognitive Impairment. 237 patients (infarct: 57; cerebral hemorrhage: 54; ruptured aneurysm of the anterior communicating artery (ACoA): 80; cerebral venous thrombosis (CVT): 46) were examined by using the GREFEX battery. The patients' test results were interpreted with a validated framework derived from normative data from 780 controls. Dysexecutive syndrome was observed in 88 (55.7%; 95%CI: 48-63.4) out of the 156 patients with full cognitive and behavioral data: 40 (45.5%) had combined behavioral and cognitive syndromes, 29 (33%) had a behavioral disorder alone and 19 (21.6%) had a cognitive syndrome al...Continue Reading

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Citations

Jan 10, 2017·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Ki Young ShinYoo-Hun Suh
Nov 7, 2019·Journal of the American Heart Association·Wai Kwong TangJong S Kim
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Oct 26, 2018·Stroke; a Journal of Cerebral Circulation·Laurent PuyUNKNOWN GRECogVASC Study Group
Nov 4, 2021·Journal of Neurology, Neurosurgery, and Psychiatry·Giuseppe ScopellitiMarco Pasi

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Software Mentioned

SAS
GREFEX

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