PMID: 2097669Jan 1, 1990Paper

The behavioral neurobiology of self-injurious behavior in rhesus monkeys

Progress in Neuro-psychopharmacology & Biological Psychiatry
G W Kraemer, A S Clarke

Abstract

1. Self-injurious behavior (SIB) is prevalent among institutionalized children, but the efficacy of current behavioral and pharmacological treatments is marginal. 2. There is evidence that SIB in humans has a neurobiological basis. A better understanding of the neurobiological factors that may promote or cause SIB is necessary for the development of effective pharmacologic treatments. 3. SIB that is similar in some respects to SIB in humans occurs in nonhuman primates that have been deprived of social experience early in life. An analysis of the "cause" of SIB suggests that it is a relatively straight-forward example of the development of neurobiological and behavioral aspects of aggressive behavior in the absence of social factors that would normally bring the behavior under environmental control. Once induced, however, it becomes environmentally autonomous and its proximal cause is neurobiological in nature. 4. There are three lines of evidence that nonhuman primate SIB is linked to malfunctions in the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems. The activity of these systems appears to be altered by psychosocial deprivation. The functional relationship between the two systems appears to be altered or abs...Continue Reading

References

Sep 1, 1978·Journal of Autism and Childhood Schizophrenia·S R SchroederJ Dalldorf
Mar 1, 1979·Journal of Autism and Developmental Disorders·S CastellsW L Nyhan
Nov 1, 1975·Archives of General Psychiatry·E C Moran, W T McKinney
Feb 18, 1977·Science·S M Antelman, A R Caggiula
Jan 1, 1986·Annals of the New York Academy of Sciences·G L Brown, F K Goodwin
Jan 1, 1986·Annals of the New York Academy of Sciences·A RoyM Linnoila
Nov 1, 1988·Acta Psychiatrica Scandinavica·A Roy, M Linnoila
Dec 3, 1985·European Journal of Pharmacology·S KorsgaardE Christensson
Oct 1, 1973·Archives of General Psychiatry·W T McKinneyJ M Davis
Aug 1, 1967·Archives of General Psychiatry·A H Green
Jan 1, 1968·Folia primatologica; international journal of primatology·G D Mitchell
Oct 1, 1968·Archives of General Psychiatry·M J Shodell, H H Reiter
Nov 5, 1981·The New England Journal of Medicine·K G LloydI H Fox
Jun 1, 1982·Pharmacology, Biochemistry, and Behavior·K Mueller, W L Nyhan
Jan 1, 1984·Neuroscience and Biobehavioral Reviews·D J Albert, M L Walsh
Apr 1, 1984·Forensic Science International : Synergy·H H HoppeP J Lincoln
Jun 1, 1983·Pharmacology, Biochemistry, and Behavior·K Mueller, W L Nyhan
Apr 1, 1984·Archives of General Psychiatry·M J RaleighA Yuwiler
Oct 1, 1982·Pharmacology, Biochemistry, and Behavior·K MuellerW L Nyhan
Jan 1, 1980·Applied Research in Mental Retardation·W L NyhanK L Jones
Apr 1, 1963·Perceptual and Motor Skills·L A ROSENBLUM, H F HARLOW

❮ Previous
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Citations

Jan 12, 1999·Neuroscience and Biobehavioral Reviews·N G SimonS Hu
Jun 6, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Charmaine HugoDan J Stein
Sep 21, 2000·Psychoneuroendocrinology·S TiefenbacherJ S Meyer
Sep 1, 1992·The Behavioral and Brain Sciences·G W Kraemer
Sep 1, 1992·The Behavioral and Brain Sciences·M L Boccia
Sep 1, 1992·The Behavioral and Brain Sciences·J P Capitanio
Sep 1, 1992·The Behavioral and Brain Sciences·L A Eiserer
Sep 1, 1992·The Behavioral and Brain Sciences·H D Ellis
Sep 1, 1992·The Behavioral and Brain Sciences·D G Freedman
Sep 1, 1992·The Behavioral and Brain Sciences·T R Insel
Sep 1, 1992·The Behavioral and Brain Sciences·B Jacobs, M J Raleigh
Sep 1, 1992·The Behavioral and Brain Sciences·J Kagan
Sep 1, 1992·The Behavioral and Brain Sciences·J K Kovach
Sep 1, 1992·The Behavioral and Brain Sciences·W A Mason
Sep 1, 1992·The Behavioral and Brain Sciences·C B Nemeroff, S H Goodman
Sep 1, 1992·The Behavioral and Brain Sciences·D Pérusse
Sep 1, 1992·The Behavioral and Brain Sciences·E A Salzen
Sep 1, 1992·The Behavioral and Brain Sciences·M Sigman, D J Siegel
Sep 1, 1992·The Behavioral and Brain Sciences·T H Svensson
Sep 1, 1992·The Behavioral and Brain Sciences·C Trevarthen
Jan 16, 2009·Development and Psychopathology·Leslie AtkinsonSheila Kerr
Apr 5, 2002·Psychological Bulletin·Rena L RepettiTeresa E Seeman
Sep 20, 1996·Annals of the New York Academy of Sciences·E F Coccaro
Sep 20, 1996·Annals of the New York Academy of Sciences·G W Kraemer, A S Clarke
Aug 27, 2013·Experimental Brain Research·Vasileios BoulougourisGiuseppe Di Giovanni
Sep 11, 2013·The Veterinary Clinics of North America. Exotic Animal Practice·Valarie V Tynes
Mar 1, 2011·Progress in Neuro-psychopharmacology & Biological Psychiatry·Antonio Preti
Jul 21, 2015·Brain, Behavior, and Immunity·Kim M LeeAndrew G MacLean
Jun 23, 2010·American Journal of Primatology·Kathy L BentsonJames C Ha
Sep 1, 1996·Biological Psychiatry·A S ClarkeG W Kraemer
Mar 25, 2008·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Johannes Rojahn, Pia Bienstein
Jan 6, 2000·Toxicology and Applied Pharmacology·J D CreminD R Smith
Mar 1, 1999·Acta Neuropsychiatrica·S Tuinier, W M Verhoeven
Aug 1, 1996·Psychiatry·Amini FariborzElizabeth Zirker Schiff
Oct 19, 2002·American Journal of Primatology·Rita U Bellanca, Carolyn M Crockett
Jun 10, 2009·Expert Opinion on Drug Safety·Partam ManalaiTeodor T Postolache
Feb 1, 2008·Psychological Reports·Antonio Preti
Jun 15, 2018·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Maya S Kummrow, Martin Brüne

❮ Previous
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