PMID: 37605May 1, 1979

The beta-adrenergic blocking agents and the treatment of glaucoma

Survey of Ophthalmology
T J Zimmerman, W P Boger

Abstract

The autonomic nervous system is divided into the parasympathetic and sympathetic systems, with three types of adrenergic receptors: alpha (smooth muscle contraction), beta1 (cardiac acceleration and fatty acid mobilization) and beta2 (smooth muscle relaxation). Substances affecting the function of the adrenergic system are the agonists or stimulators, which mimic the effects of endogenous norepinephrine or epinephrine, and antagonists or blockers, which block the receptors and prevent stimulation by the agonists. Autonomic stimulation in the eye mediates various changes which apparently affect outflow facility and rate of formation of aqueous humor. Alteration of either or both of these factors by autonomic agonists or antagonists may have a direct or an indirect effect on intraocular pressure. Beta-adrenergic blocking substances have been used to treat a variety of diseases. Some of the effects of these drugs are attributable to properties other than beta blockade, such as intrinsic sympathomimetic activity and local anaesthetic activity. Side effects of this class of drugs require caution in cases of congestive heart failure and in asthmatics. Autonomic agents used in the treatment of ocular hypertension and glaucoma include ...Continue Reading

References

Aug 28, 1976·British Medical Journal·D TrashK Christopher
Jan 1, 1978·The Journal of Pharmacy and Pharmacology·P VermeijP A van Zwieten
Oct 1, 1978·Experimental Eye Research·A H Neufeld
May 1, 1977·The British Journal of Ophthalmology·K Wettrell, M Pandolfi
Aug 1, 1978·Experimental Eye Research·M E YablonskiB Becker
Sep 1, 1978·American Journal of Ophthalmology·A Ohrström, M Pandolfi
Oct 1, 1976·The British Journal of Ophthalmology·A Garner, A H Rahi
Nov 1, 1975·Neurology·E S Tolosa, R B Loewenson
Mar 1, 1973·The British Journal of Ophthalmology·J Vale, C I Phillips
May 26, 1973·British Medical Journal·E B Raftery, A M Denman
May 11, 1974·British Medical Journal·R Felix, F A Ive
Sep 1, 1971·European Journal of Clinical Pharmacology·H J GilfrichR F Nicolescu
Dec 14, 1974·British Medical Journal·E B Raftery
Dec 1, 1966·The Anatomical Record·A M Laties, D Jacobowitz
Jan 1, 1971·Zeitschrift für Zellforschung und mikroskopische Anatomie·B Ehinger
May 1, 1969·Annals of Internal Medicine·G Das, M Krieger
Apr 1, 1967·The British Journal of Ophthalmology·C I PhillipsD J Rowlands
Nov 16, 1963·British Medical Journal·G E PAGET
May 9, 1964·British Medical Journal·B N PRICHARD
May 31, 1906·The Journal of Physiology·H H Dale

Citations

Jan 1, 1985·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M Araie, M Takase
Jan 1, 1984·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·N N ShareC A Stone
Jan 1, 1982·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E Stenkula, K Wettrell
Jan 1, 1989·Pharmacology & Therapeutics·M F Sugrue
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J A Nathanson
Jan 1, 1996·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·W C Stewart
Mar 17, 2009·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Yangfan YangMinbin Yu
Dec 1, 1982·The British Journal of Ophthalmology·G E Trope, B Clark
Oct 1, 1983·The British Journal of Ophthalmology·M K Tutton, R J Smith
Apr 1, 1983·The British Journal of Ophthalmology·S Andréasson, K M Jensen
Jan 1, 2008·Personalized Medicine·Duska J SidjaninRussell A Wilke
Oct 1, 1981·American Journal of Ophthalmology·M YalonM Blumenthal
Mar 1, 2011·Expert Opinion on Emerging Drugs·Anne J Lee, Ivan Goldberg
Mar 1, 1981·Ophthalmology·R P LeBlanc, G Krip
Mar 1, 1981·Ophthalmology·W P Boger, D S Walton
May 1, 1980·Ophthalmology·R P WilsonE Poryzees
Jul 28, 2011·The Ocular Surface·Charles S TresslerMichael A Lemp
Sep 1, 2015·The Veterinary Clinics of North America. Small Animal Practice·Anthony F AlarioStefano Pizzirani
Jun 5, 2007·Pharmacotherapy·Jaekyu Shin, Julie A Johnson
Dec 1, 1983·Survey of Ophthalmology·T J ZimmermanJ Hetherington
Dec 1, 1983·Survey of Ophthalmology·W P Boger
May 1, 1982·Australian Journal of Ophthalmology·K D Frumar, R McGuinness
Feb 18, 2012·Current Eye Research·Cheng-Chun PengAnuj Chauhan
Mar 19, 2011·Trends in Pharmacological Sciences·Michael J A Walker
Mar 1, 1991·Journal of Pharmaceutical Sciences·T Kaila
Aug 9, 2011·Current Opinion in Allergy and Clinical Immunology·Flavio MantelliStefano Bonini
Dec 22, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fatima Zahra BamouZsolt Szakonyi
Apr 3, 2018·American Journal of Pharmaceutical Education·João Paulo S Fernandes
Nov 1, 1986·The Journal of Pharmacy and Pharmacology·M AlkondonP Sen
Aug 1, 1980·Acta Ophthalmologica·G K KrieglsteinW Leydhecker
May 7, 2019·Microsystems & Nanoengineering·Hyunsu ParkHyowon Lee

Related Concepts

Adrenergic beta-Antagonists
Metazoa
Aqueous Flare
Autonomic Nervous System
Canis familiaris
Dose-Response Relationship, Drug
Use-Effectiveness
Eye
Glaucoma
Physiologic Intraocular Pressure

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.