The biallelic a mating type locus of Ustilago maydis: remnants of an additional pheromone gene indicate evolution from a multiallelic ancestor

Molecular & General Genetics : MGG
M UrbanM Bölker

Abstract

The a mating type locus of Ustilago maydis contains the structural genes for a pheromone-based cell recognition system that governs fusion of haploid cells. The locus exists in two alleles, termed a1 and a2. We have completed the analysis of the nucleotide sequences unique to a1 and a2. Within these dissimilar regions we find two short patches of DNA sequence similarity. Interestingly, one of these segments corresponds to the transcribed region of the a1 pheromone precursor. As a result of multiple nucleotide exchanges this sequence does not code for a functional product. The existence of a second pheromone gene in the a2 allele suggests that the present locus had a multiallelic ancestor. In addition, we describe the presence of two additional genes in the a2 allele. We have investigated the role of these genes during mating and pathogenic development and speculate that they might affect mitochondrial inheritance.

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Citations

Oct 16, 1996·Molecular & General Genetics : MGG·T SpelligR Kahmann
Apr 24, 1996·Molecular & General Genetics : MGG·M UrbanM Bölker
Jan 1, 2000·Molecular Plant Pathology·A GrandelJ Kämper
Apr 15, 1997·The EMBO Journal·E RegenfelderR Kahmann
Nov 8, 2005·The Plant Cell·Jan SchirawskiRegine Kahmann
Apr 1, 2014·International Journal of Systematic and Evolutionary Microbiology·Juliana Velasco de Castro OliveiraDiego Mauricio Riaño-Pachón
Mar 1, 1996·FEMS Microbiology Reviews·E Kothe
Jul 7, 2011·FEMS Microbiology Reviews·Evelyn VollmeisterMichael Feldbrügge
Nov 30, 2004·Advances in Applied Microbiology·María D García-Pedrajas, Scott E Gold
Jul 4, 2008·Acta Microbiologica Et Immunologica Hungarica·Erika Kothe
Jun 4, 2010·Proceedings. Biological Sciences·Gildas MerceronEllen Schulz
May 10, 2005·Eukaryotic Cell·M Gabriela RocaNick D Read
May 29, 2010·Microbiology and Molecular Biology Reviews : MMBR·Soo Chan LeeJoseph Heitman
Nov 21, 2012·Journal of Evolutionary Biology·B P S Nieuwenhuis, D K Aanen
Jun 4, 2020·International Journal of Molecular Sciences·Hector MendozaJan Schirawski
Oct 1, 2004·The New Phytologist·Regine Kahmann, Jörg Kämper
Jun 24, 2006·Fungal Genetics and Biology : FG & B·Guus BakkerenJames W Kronstad

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