The Biocompatibility of Dental Graded Nano-Glass-Zirconia Material After Aging

Nanoscale Research Letters
Ting SunRenfa Lai

Abstract

ᅟ: A graded nano-glass/zirconia (G/Z) system has been developed via the infiltration of nano-glass into a nano-zirconia surface, which is advantageous for robust core-veneer bonds. The aging issue is a key for yttrium-stabilized tetragonal zirconia polycrystals (Y-TZPs), and therefore, it is necessary to evaluate the influence of aging degradation on the biocompatibility of G/Z systems before their possible clinical application. Herein, such biocompatibility testing was performed with human gingival fibroblasts (HGFs) seeded onto unaged/aged G/Z and Y-TZP for 2-72 h. Assessments included an oral mucous membrane irritation test in conjunction with analyses of cell viability, cell adhesion, and oxidative stress responses. Significant metabolic decreases in aged G/Z- and Y-TZP-treated cells were observed at 72 h. G/Z did not elicit any significant differences in cell viability compared with Y-TZP over 72 h both before and after aging. The oxidative stress data for the aged G/Z- and Y-TZP-treated cells showed a significant increase at 72 h. The G/Z specimens did not elicit any significant differences in ROS production compared with Y-TZP over 72 h both before and after aging. The cell adhesion rates of both G/Z and Y-TZP increased ...Continue Reading

References

Jul 13, 2002·Journal of Biomedical Materials Research·Percy MilledingStig Karlsson
Oct 31, 2003·The Journal of Prosthetic Dentistry·Regina L W MesserSerge Bouillaguet
Apr 8, 2004·Journal of Periodontology·Antonio ScaranoAdriano Piattelli
Jul 31, 2007·Dental Materials : Official Publication of the Academy of Dental Materials·Isabelle Denry, J Robert Kelly
Oct 24, 2007·Acta Odontologica Scandinavica·Camilla AhlgrenKrister Nilner
Feb 10, 2010·The Journal of Prosthetic Dentistry·Maged K Etman, M J Woolford
Mar 5, 2010·Journal of Dental Research·Y ZhangB R Lawn
Aug 6, 2010·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Maria Francesca SfondriniCatherine Klersy
Dec 20, 2011·Acta Biomaterialia·Yu ZhangDenzil Zhang
Jun 29, 2013·Dental Materials : Official Publication of the Academy of Dental Materials·C Brunot-GohinC Egles
Jun 4, 2014·Journal of Tissue Engineering and Regenerative Medicine·Jean-Luc DuvalChristophe Egles
Jan 13, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Masanao InokoshiJozef Vleugels
Mar 31, 2015·Journal of the Mechanical Behavior of Biomedical Materials·Ruoyu LiuLongquan Shao
Apr 25, 2016·Biomedizinische Technik. Biomedical Engineering·Waleed M S Al QahtaniLutz Scheideler
Jul 20, 2016·Journal of Dental Research, Dental Clinics, Dental Prospects·Mahmoud BahariAli Morsali Ahari
Oct 12, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Márcia BorbaPaulo F Cesar
Jan 5, 2017·Journal of Periodontal & Implant Science·Céline Brunot-GohinChristophe Egles
Aug 23, 2017·Journal of Prosthodontic Research·Karthik SivaramanDhanasekar Balakrishnan

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Citations

Sep 6, 2019·Polymers·María Rizo-GorritaJosé-Luis Gutiérre-Pérez

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Methods Mentioned

BETA
Assay
scanning electron microscopy
Fluorescence
fluorescence microscopy

Software Mentioned

SPSS

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