The biology of burn injury

Experimental Dermatology
Lars H EversPeter Mailänder

Abstract

Burn injury is a complex traumatic event with various local and systemic effects, affecting several organ systems beyond the skin. The pathophysiology of the burn patient shows the full spectrum of the complexity of inflammatory response reactions. In the acute phase, inflammation mechanism may have negative effects because of capillary leak, the propagation of inhalation injury and the development of multiple organ failure. Attempts to mediate these processes remain a central subject of burn care research. Conversely, inflammation is a necessary prologue and component in the later-stage processes of wound healing. In this review, we are attempting to present the current science of burn wound pathophysiology and wound healing. We also describe the evolution of innovative strategies for burn management.

Associated Clinical Trials

References

Jan 1, 1992·World Journal of Surgery·T LundR K Reed
Jan 1, 1992·World Journal of Surgery·E E Tredget, Y M Yu
Dec 1, 1990·The Journal of Trauma·P A Ward, G O Till
Feb 1, 1986·The Journal of Trauma·P B ThompsonS Abston
Aug 14, 1968·Annals of the New York Academy of Sciences·C R Baxter, T Shires
May 1, 1984·The Journal of Clinical Investigation·R L Ruff, D Secrist
Jan 1, 1982·Critical Care Medicine·N Nishimura, N Hiranuma
Jan 22, 1994·Lancet·M J Muller, D N Herndon
Dec 19, 1996·The New England Journal of Medicine·W E Mitch, A L Goldberg
Oct 27, 1997·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·F P Rivara
Feb 25, 1998·Archives of Physical Medicine and Rehabilitation·D M St-PierreD R Garrel
Jan 23, 1999·Burns : Journal of the International Society for Burn Injuries·L W ChenS C Chen
Mar 26, 1999·The Journal of Surgical Research·J T MurphyJ W Horton
Jan 25, 2000·The Journal of Surgical Research·J D PellegriniC Miller-Graziano
Jan 25, 2002·Journal of Cellular Physiology·Eri Iwai-KanaiShigetake Sasayama
Mar 21, 2002·Critical Care Medicine·D Jean WhiteJureta W Horton
Apr 20, 2002·World Journal of Surgery·Richard H TurnageHelen Yin
Jun 8, 2002·Burns : Journal of the International Society for Burn Injuries·Takahide MaekawaOsafumi Yuge
Aug 16, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·Marcus SpiesSteven E Wolf
May 1, 1953·The British Journal of Surgery·D M JACKSON
Oct 1, 1950·British Journal of Plastic Surgery·M J KYLE, A B WALLACE
Apr 6, 2005·Proceedings of the National Academy of Sciences of the United States of America·Katie E PadfieldA Aria Tzika
May 14, 2005·Critical Care Medicine·Deborah L CarlsonBrett P Giroir
Aug 20, 2005·The International Journal of Biochemistry & Cell Biology·Clifford PereiraDavid N Herndon
Aug 30, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Loukas G AstrakasA Aria Tzika
Sep 10, 2005·The Journal of Burn Care & Rehabilitation·Louis J Magnotti, Edwin A Deitch
Nov 10, 2005·The Journal of Burn Care & Rehabilitation·Matthew B KleinNicole S Gibran
Apr 20, 2006·Journal of Science and Medicine in Sport·Judith M ConnJulie Gilchrist
May 20, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Robert MaileBruce A Cairns
Jan 10, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Jennifer BlumettiGary F Purdue
Jun 7, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Andrew J A HollandAnn K Guiffre
Aug 13, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Haifeng ZhuFerid Murad
Jan 9, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Leila CuttleRoy M Kimble

❮ Previous
Next ❯

Citations

Nov 1, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yiorgos ApidianakisLaurence G Rahme
Sep 21, 2013·Burns : Journal of the International Society for Burn Injuries·Steven G StrangOscar J F Van Waes
Dec 4, 2014·The International Journal of Biochemistry & Cell Biology·Philip Arandjelovic, Pritinder Kaur
Feb 13, 2016·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Hui-Wen ChiuYung-Ho Hsu
Feb 14, 2016·Medicina intensiva·M Sánchez-SánchezM J Asensio
Feb 26, 2016·Burns : Journal of the International Society for Burn Injuries·Matthew K McIntyreDavid M Burmeister
Aug 3, 2013·The Urologic Clinics of North America·Andrew J Chang, Steven B Brandes
Jan 24, 2013·Burns : Journal of the International Society for Burn Injuries·Yun-Jung LeeIn-Suk Kwak
Jun 1, 2012·Burns : Journal of the International Society for Burn Injuries·Michelle KiserAnthony Charles
Mar 22, 2012·Advanced Drug Delivery Reviews·Scott P NicholsMark H Schoenfisch
Jan 8, 2016·Burns : Journal of the International Society for Burn Injuries·Yanbin GaoGuifang Wang
Aug 14, 2012·Medicinal Research Reviews·Robert R RigorSarah Y Yuan
Jul 16, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J SongJ D Z Chen
Aug 15, 2015·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Yunfei ChiQinxue Zhang
Jan 30, 2015·Burns : Journal of the International Society for Burn Injuries·Peter D DrummondMark W Fear
Jan 22, 2013·Journal of Ethnopharmacology·Mariane Arnoldi SilvaJuliano Ferreira
Dec 9, 2014·International Journal of Molecular Medicine·Yonghui Yu, Jiake Chai
Jul 20, 2014·Carbohydrate Polymers·Sónia P MiguelIlídio J Correia
Mar 19, 2013·European Journal of Pharmacology·Helen LaycockIstvan Nagy
Dec 3, 2014·Burns : Journal of the International Society for Burn Injuries·Liangyun ShenQian Tan
Sep 8, 2016·Advances in Wound Care·Jeffrey E ThatcherJ Michael DiMaio
Mar 31, 2016·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Ryan S ChiangAlan D Widgerow
May 31, 2016·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Daniel C RoyRobert J Christy
May 14, 2016·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Roos E MarckEsther Middelkoop
Sep 10, 2016·Tissue Engineering. Part B, Reviews·Dorothée GirardAlexis Desmoulière
Oct 30, 2014·Acta Cirúrgica Brasileira·Sarita Mac CornickAlfredo Gragnani
Feb 13, 2014·Journal of Burn Care & Research : Official Publication of the American Burn Association·Rose E MarckRoelf S Breederveld
May 9, 2015·Cell Transplantation·Carolina Caliari-OliveiraJulio César Voltarelli
Apr 2, 2017·Hand Clinics·Mary Claire Manske, Douglas P Hanel
Apr 13, 2013·The Annals of Otology, Rhinology, and Laryngology·Alexander T HillelAdam M Klein
Mar 20, 2018·Platelets·Roos E MarckEsther Middelkoop
Feb 16, 2017·Journal of Burn Care & Research : Official Publication of the American Burn Association·Ruiqi LiuYing Cen
Jul 24, 2013·Journal of Burn Care & Research : Official Publication of the American Burn Association·Quan HuZhi-Yong Sheng
Nov 26, 2013·Journal of Burn Care & Research : Official Publication of the American Burn Association·Meenakshi RaniMartin G Schwacha
Jul 9, 2016·Journal of Burn Care & Research : Official Publication of the American Burn Association·Zhenggang GuoPing Li
May 18, 2016·Journal of Burn Care & Research : Official Publication of the American Burn Association·Jennifer K PlichtaKatherine A Radek

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Burns : Journal of the International Society for Burn Injuries
I OnoF Kaneko
The Journal of Pain : Official Journal of the American Pain Society
Gretchen J SummerJon D Levine
Journal of Burn Care & Research : Official Publication of the American Burn Association
Jeffrey I L Saffle
Burns : Journal of the International Society for Burn Injuries
Arti PariharSatyanarayan Bhat
© 2021 Meta ULC. All rights reserved