The biomechanical evaluation of calcium phosphate cements for use in vertebroplasty

Journal of Neurosurgery. Spine
Suk-Joo HongYeon Soo Kim

Abstract

The authors evaluate the biomechanical properties of vertebral bodies (VBs) stabilized with calcium phosphate (CaP) cements for use in vertebroplasty in comparison with polymethylmethacrylate (PMMA). In the first phase of the study, 73 VBs (T3-L2; thoracic region [T3-8] and thoracolumbar region [T9-L2]) were collected from seven fresh human cadavers. Compression tests were performed before and after vertebroplasty using PMMA (compression strength 80 MPa) and three kinds of CaP cements-CaP1 (5 MPa), CaP2 (20 MPa), and CaP3 (50 MPa). The authors compared the maximal compression loads (MCLs) and stiffness before and after vertebroplasty in each of the four cement groups. In the second phase of the study, 18 paired spinal units (PSUs) were collected from three fresh human cadavers, and the authors injected two types of cement selected from the first phase of the study into the lower level of six PSUs. They compared the MCLs of the untreated and two treated groups (there were six PSUs in each type of group) to analyze the tendency of inducing compression fractures in the upper level of the PSUs. The MCLs of the PMMA-injected vertebrae were significantly increased after vertebroplasty. The MCL levels of the CaP3-injected vertebrae an...Continue Reading

References

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Citations

Mar 21, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H D HeoS M Oh
Jul 21, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Luis Alvarez GalovichMaria Teresa Carrascal Morillo
May 2, 2008·Journal of Neurosurgery. Spine·Robert J OaklandRichard M Hall
Feb 26, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Rainer GumpertPaul Puchwein
Apr 7, 2011·Musculoskeletal Surgery·Andrea PiazzollaGiuseppe Solarino
Jun 9, 2007·Neurosurgery Clinics of North America·Ivan ChengMichael S Wildstein
Aug 19, 2009·Journal of Materials Science. Materials in Medicine·D O'BrienS Murphy
Aug 14, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Sebastian SchützenbergerC Fialka

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Methods Mentioned

BETA
percutaneous vertebroplasty

Software Mentioned

BoneSource

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