The blood pressure-induced diameter response of retinal arterioles decreases with increasing diabetic maculopathy

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Christian Alcaraz FrederiksenT Bek

Abstract

The aim of the study was to compare the diameter response of retinal arterioles and retinal thickness in patients with different stages of diabetic maculopathy during an increase in the arterial blood pressure. Four groups each consisting of 19 individuals were studied. Group A consisted of normal individuals and groups B-D consisted of type 2 diabetic patients matched for diabetes duration, age, and gender, and characterized by: Group B no retinopathy, Group C mild retinopathy, Group D maculopathy not requiring laser treatment. The diameter changes of a large retinal arteriole were measured using the Retinal Vessel Analyzer (RVA, Imedos, Germany) before, during, and after an increase in the blood pressure induced by isometric exercise. Additionally, the retinal thickness was measured using optical coherence tomography scanning. The arterioles contracted during isometric exercise in normal persons (diameter response: -0.70+/-0.48%) and in patients with no retinopathy (-1.15+/-0.44%), but dilated in patients with mild retinopathy (0.41+/-0.49%) and diabetic maculopathy (0.54+/-0.44%), p=0.01. Retinal thickness was normal in Group A (260+/-5.0 microm), Group B (257+/-4.5 microm), and Group C (253+/-4.4 microm), but was significan...Continue Reading

References

Feb 1, 1975·Diabetologia·E M KohnerC J Bulpitt
Jul 1, 1982·Ophthalmology·S H SinclairS S Schwartz
Apr 1, 1996·The British Journal of Ophthalmology·J E GrunwaldC E Riva
Jul 1, 1996·Diabetes Care·K B StansberryA I Vinik
Apr 1, 1997·Diabetes·L SchmettererM Wolzt
Apr 1, 1997·The British Journal of Ophthalmology·J K KristinssonE Stefánsson
Oct 3, 2000·Ophthalmic Research·C Delaey, J Van De Voorde
Oct 26, 2000·The British Journal of Ophthalmology·K PolakL Schmetterer
Feb 5, 2002·Advances in Physiology Education·H S Badeer
Apr 10, 2002·American Journal of Hypertension·Søren Tang KnudsenCarl Erik Mogensen
Oct 22, 2002·American Journal of Physiology. Endocrinology and Metabolism·S T KnudsenL M Rasmussen
Dec 6, 2002·Biomedizinische Technik. Biomedical Engineering·B U Seifertl, W Vilser
Jul 20, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Peter JeppesenToke Bek
Sep 29, 2004·Diabetes Care·Donald S FongRonald Klein
Sep 30, 2004·Acta Ophthalmologica Scandinavica·Peter Jeppesen, Toke Bek

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Citations

Dec 20, 2007·Naunyn-Schmiedeberg's Archives of Pharmacology·Taisuke NakazawaKunio Ishii
Feb 13, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Toke BekPeter Jeppesen
Mar 19, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jung Hyun ParkHyeong Gon Yu
Oct 5, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Toke Bek
Nov 12, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Peter Skov JensenToke Bek
Nov 20, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Wendy W HarrisonAnthony J Adams
Jun 8, 2010·Diabetologia·K M GoodingA C Shore
Apr 2, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Line PedersenToke Bek
Jun 4, 2014·Current Eye Research·Doreen SchmidlAlina Popa-Cherecheanu
Nov 13, 2013·Current Eye Research·Marion R MunkUrsula Schmidt-Erfurth
Dec 1, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Musa Yasin KayaToke Bek
Jun 15, 2007·Diabetic Medicine : a Journal of the British Diabetic Association·S T KnudsenP L Poulsen
Jan 28, 2009·Survey of Ophthalmology·Cong SunTien Y Wong
May 1, 2007·Journal of the American Society of Hypertension : JASH·Søren Tang KnudsenPer Løgstrup Poulsen
May 12, 2010·Clinical & Experimental Ophthalmology·Mohamed DiraniJoan Cunningham
Dec 20, 2008·Acta Ophthalmologica·Martin VintenMichael Larsen
Jul 31, 2013·Progress in Retinal and Eye Research·Toke Bek
Jun 9, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Line Petersen, Toke Bek
Feb 3, 2018·Eye·Sophie D West, Chris Turnbull
Jan 12, 2010·Retina·Zvia Burgansky-EliashAdiel Barak
Sep 24, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Peter JeppesenToke Bek
Aug 10, 2017·Current Diabetes Reports·Toke Bek
Jul 29, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Line Petersen, Toke Bek
Jul 6, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yasmin El DabaghToke Bek
Feb 26, 2019·Acta Ophthalmologica·Toke Bek
Mar 9, 2021·Investigative Ophthalmology & Visual Science·Toke Bek, Signe Krejberg Jeppesen
Sep 2, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Somar M HasanDaniel Meller
Dec 6, 2019·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Kathrine Kleis Tilma, Toke Bek

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