PMID: 11333121May 3, 2001Paper

The body site distribution of melanocytic naevi in 6-7 year old European children

Melanoma Research
P AutierEPIMEL

Abstract

The number and size of melanocytic naevi are the main predictors of cutaneous melanoma. Naevus development per unit of skin surface is greatest during childhood. We assessed the body distribution of naevi 2-4.9 mm and > or = 5 mm in 649 European children aged 6-7 years old from Brussels (Belgium), Bochum (Germany), Lyon (France) and Rome (Italy). The numbers of naevi 2-4.9 mm and naevi > or = 5 mm were strongly correlated, especially on the trunk. For naevi 2-4.9 mm, the highest relative densities were found on the face, back, shoulders and the external surface of the arms. The lowest relative densities were found on the hands, legs, feet and abdomen. The relative density of naevi > or = 5 mm was higher on the trunk than on any other body site. Similar body distributions were observed in both sexes and at each centre. The body site distribution of naevi 2-4.9 mm seemed to parallel the usual sun exposure patterns of young European children. It is suggested that the development of naevi > or = 5 mm might be a marker of the vulnerability of melanocytes to the harmful effects of solar radiation. Vulnerability would be maximal on the back, and would decrease from proximal to distal skin areas, with melanocytes of the hands and feet ...Continue Reading

References

Nov 1, 1992·Cancer Causes & Control : CCC·A Green
Jun 14, 1986·British Medical Journal·A J SwerdlowD J Hole
Dec 1, 1986·International Journal of Epidemiology·D K Pearl, E L Scott
Jan 10, 1985·The New England Journal of Medicine·M H GreeneM C Fraser
Dec 3, 1994·Lancet·S L HarrisonI Wronski
Feb 15, 1994·American Journal of Epidemiology·D R English, B K Armstrong
Jan 1, 1994·Journal of the American Academy of Dermatology·J W KellyB J Tate
Jan 21, 1993·International Journal of Cancer. Journal International Du Cancer·A GreenN Martin
May 25, 1996·BMJ : British Medical Journal·R J PerryD L Plummer
Dec 11, 1995·International Journal of Cancer. Journal International Du Cancer·D WhitemanA Green
Jan 6, 1997·International Journal of Cancer. Journal International Du Cancer·D C WhitemanA C Green
May 14, 1997·JAMA : the Journal of the American Medical Association·M A TuckerW H Clark
Mar 1, 1997·Current Opinion in Oncology·M Berwick, A Halpern
Oct 10, 1998·International Journal of Cancer. Journal International Du Cancer·J M Elwood, R P Gallagher
Jan 26, 1999·Melanoma Research·W A RobinsonD Norris
Jan 29, 1999·Archives of Dermatology·S L HarrisonR MacLennan

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Citations

Jun 19, 2008·Archives of Dermatology·Heidi H KongChristine Chevreau
Jun 11, 2005·Cancer Causes & Control : CCC·Victor SiskindAdèle C Green
Nov 13, 2008·American Journal of Epidemiology·Susan A OliveriaAllan C Halpern
Jun 5, 2003·Journal of the National Cancer Institute·David C WhitemanAdèle C Green
Aug 4, 2005·Journal of the National Cancer Institute·Philippe AutierJean-François Doré
Oct 13, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Athena T DoddLori A Crane
Jun 11, 2014·PLoS Medicine·Marina KvaskoffMarie-Christine Boutron-Ruault
Apr 25, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Pinar OztasNuran Alli
Sep 13, 2011·Progress in Biophysics and Molecular Biology·Rüdiger Greinert, Mathieu Boniol
Mar 19, 2008·Actas dermo-sifiliográficas·J M CasanovaA Font
Dec 16, 2005·The Journal of Investigative Dermatology·Scott R FlorellSancy A Leachman
Mar 28, 2008·The British Journal of Dermatology·A ScopeA C Halpern
Oct 31, 2009·Clinical and Experimental Dermatology·S YarakF A de Almeida
Aug 24, 2013·International Journal of Dermatology·Ivette M Sosa-SedaRogelio Mercado
Apr 11, 2019·Melanoma Research·Philippe Autier, Jean-François Doré
Nov 22, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·A Buendía-EismanS Serrano-Ortega
Feb 10, 2016·Journal of the National Cancer Institute·David C GibbsUNKNOWN GEM Study Group
Aug 15, 2003·International Journal of Cancer. Journal International Du Cancer·David C WhitemanMaria-Celia Hughes
Oct 3, 2013·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marina KvaskoffDavid C Whiteman

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