PMID: 8273982Feb 1, 1994

The booster effect in two-step tuberculin testing among young adults in Montreal

Annals of Internal Medicine
R MenziesY St Germain

Abstract

No consensus exists regarding the definition and interpretation of a significant boosting reaction after sequential tuberculin testing. The booster phenomenon is thought to represent remote tuberculous infection where tuberculin reactivity has waned, but it has also been described among persons with previous exposure to other mycobacteria or Bacille Calmette-Guérin (BCG) vaccine. We studied the factors affecting the booster phenomenon among Canadian-born young adults to determine the definition that would maximize sensitivity and specificity of a positive booster reaction in these persons. Point-prevalence survey of initial tuberculin reactions and response to repeated tuberculin testing after 1 to 4 weeks. Community-based study of all students entering health professional training programs at six post-secondary institutions. In 1989, 1990, and 1991, students completed self-administered questionnaires, underwent two-step tuberculin testing with purified protein derivative-tuberculin (PPD-T), and had their childhood BCG vaccination status verified. In 1991, students were also tested with purified protein derivative-Battey (PPD-B) (for Mycobacterium intracellulare). Overall, 74 students (5.2%) had positive booster reactions, whic...Continue Reading

Citations

Jan 12, 1995·The New England Journal of Medicine·Dick MenziesM Fitzgerald
Apr 11, 1996·The New England Journal of Medicine·T A KenyonKenneth G Castro
Sep 30, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dick Menzies
Sep 14, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nina M LarsenHenry M Blumberg
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Victor HerreraNiaz Banaei
May 25, 1999·Journal of Occupational and Environmental Medicine·K M HallakA V Neale
Jan 9, 2007·Respirology : Official Journal of the Asian Pacific Society of Respirology·Kazue HiguchiYukie Sekiya
Nov 13, 2004·Clinical and Diagnostic Laboratory Immunology·Edward W TaggartChristine M Litwin
Aug 1, 1997·American Journal of Respiratory and Critical Care Medicine·C D WellsS V Goldberg
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·Dick Menzies
Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·K Al ZahraniDick Menzies
Nov 26, 2002·American Journal of Respiratory and Critical Care Medicine·Dick MenziesCanadian Collaborative Group in Nosocomial Transmission of Tuberculosis
Jul 16, 2010·BMC Infectious Diseases·Carla A Winston, Thomas R Navin
Jun 1, 2010·Journal of Immune Based Therapies and Vaccines·Rajpal S KashyapHatim F Daginawala
Jun 28, 2007·Journal of Addictive Diseases·Shobha SwaminathanMarc N Gourevitch
Nov 1, 1994·American Journal of Public Health·T R Frieden
Jun 1, 1995·American Journal of Public Health·N Adhikari, R Menzies
Jun 12, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Susan Shin-Jung LeeYao-Shen Chen
Apr 12, 2012·The American Journal of Tropical Medicine and Hygiene·C Scott MahanW Henry Boom
Jan 10, 2014·BMC Medical Informatics and Decision Making·Marie-Claude RousseauMariam El-Zein
May 15, 2013·Journal of Infection and Public Health·M A IslerP Brassard
Aug 21, 2012·Enfermedades infecciosas y microbiología clínica·Mercedes García-GasallaIsabel Mir-Villadrich
Apr 1, 2011·Enfermedades infecciosas y microbiología clínica·Miguel Santín Cerezales, José Domínguez Benítez
Apr 2, 2011·Mayo Clinic Proceedings·Irene G Sia, Mark L Wieland
Aug 1, 1996·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·D MenziesT Tannenbaum
Oct 1, 1996·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M A MillerIda M Onorato
Feb 1, 1996·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·P Miret-CuadrasS Juncosa
Nov 4, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·K HizelF Aktas
Nov 1, 1994·American Journal of Public Health·D L Patrick
Mar 10, 2001·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M L García-GarcíaJ L Valdespino-Gómez
Jan 8, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ramazan KeskinerBasak Dokuzoguz
Jan 8, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Abdulrahman M Al Mazrou
May 4, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Nobuyuki HaradaToru Mori
Feb 3, 2000·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M Swinker
Oct 4, 2007·International Journal of Dermatology·Lily N Clark, Mark Lebwohl
Jul 3, 1999·Annals of Internal Medicine·D F Hoft, J M Tennant

Related Concepts

BCG Vaccine
False Positive Reactions
Tuberculin Test
Odds Ratio

Related Feeds

Related Papers

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Abdulrahman M Al Mazrou
American Journal of Respiratory and Critical Care Medicine
Dick Menzies
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
R E HuebnerS A Barnes
Anales españoles de pediatría
C Loza CortinaA Ramos Perez
© 2021 Meta ULC. All rights reserved