The BOSS Study. Determining the incidence and clinical outcomes of uncommon conditions and events in orthopaedic surgery.

Bone & Joint Open
Daniel C PerryMarian Knight

Abstract

There is widespread variation in the management of rare orthopaedic disease, in a large part owing to uncertainty. No individual surgeon or hospital is typically equipped to amass sufficient numbers of cases to draw robust conclusions from the information available to them. The programme of research will establish the British Orthopaedic Surgery Surveillance (BOSS) Study; a nationwide reporting structure for rare disease in orthopaedic surgery. The BOSS Study is a series of nationwide observational cohort studies of pre-specified orthopaedic disease. All relevant hospitals treating the disease are invited to contribute anonymised case details. Data will be collected digitally through REDCap, with an additional bespoke software solution used to regularly confirm case ascertainment, prompt follow-up reminders and identify potential missing cases from external sources of information (i.e. national administrative data). With their consent, patients will be invited to enrich the data collected by supplementing anonymised case data with patient reported outcomes.The study will primarily seek to calculate the incidence of the rare diseases under investigation, with 95% confidence intervals. Descriptive statistics will be used to descr...Continue Reading

References

Feb 17, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Marian KnightPeter Brocklehurst
Nov 18, 2011·BMJ : British Medical Journal·Timothy J BradnockUNKNOWN BAPS-CASS
Jun 20, 2013·BMJ : British Medical Journal·Patrick L ErginaUNKNOWN IDEAL Group
Apr 29, 2016·BMJ : British Medical Journal·Daniel C PerryMatthew L Costa
May 13, 2019·Journal of Biomedical Informatics·Paul A HarrisUNKNOWN REDCap Consortium

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Citations

Aug 31, 2020·The Bone & Joint Journal·Daniel C Perry, Matthew Costa
Aug 3, 2021·The Bone & Joint Journal·Joanna CravenDaniel C Perry

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Software Mentioned

REDCap
IDEAL
BOSS
REDCap Electronic Data Capture platform
UKOSS

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