PMID: 3748449Jul 24, 1986Paper

The brain fibroblast growth factor (FGF) is localized in neurons

Neuroscience Letters
B PettmannM Sensenbrenner

Abstract

The physiological role of fibroblast growth factor (FGF), like many other characterized growth factors, is poorly understood. Therefore, it would be useful to know in which cell type this growth factor is present. Using monoclonal and polyclonal antibodies against FGF, we have localized this molecule in rat brain. Interestingly, FGF is found exclusively in neuronal cells. Since FGF stimulates the proliferation and maturation of glial cells in vitro, its involvement in the interaction between neuronal and glial cells in vivo is likely. A role in the triggering of reactive gliosis can also be hypothesized.

References

Aug 12, 1976·The New England Journal of Medicine·R Ross, J A Glomset
Oct 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·F EschR Guillemin
Sep 9, 1985·FEBS Letters·B PettmannG Labourdette
Dec 17, 1985·Biochemical and Biophysical Research Communications·F EschR Guillemin
Oct 1, 1980·Physiological Reviews·H Thoenen, Y A Barde
Feb 1, 1984·European Journal of Biochemistry·J Ciesielski-TreskaD Aunis
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M Fisher
Jan 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·K A ThomasS Fitzpatrick
Nov 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·D GospodarowiczP Böhlent
Jan 1, 1982·Analytical Biochemistry·R HawkesJ Gordon
Nov 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·K A OSTERBERG, L W WATTENBERG
Jan 1, 1964·International Review of Neurobiology·C D CLEMENTE

❮ Previous
Next ❯

Citations

Apr 1, 1996·Journal of Neuroscience Research·D A Muir, D A Compston
Nov 15, 1996·Journal of Neuroscience Research·J B GrinspanD Pleasure
Jan 1, 1990·Journal of Neuroscience Research·B RogisterG Moonen
Sep 1, 1990·Journal of Neuroscience Research·S TorelliM Presta
Oct 1, 1993·Journal of Neuroscience Research·R Hardy, R Reynolds
Jan 1, 1997·Acta neurochirurgica·H KobayashiT Kubota
Nov 14, 1994·Brain Research·J WangK S Bankiewicz
Mar 1, 1990·Brain Research. Developmental Brain Research·M SebbenA Dumuis
Nov 19, 1991·Brain Research. Developmental Brain Research·C E HillI A Hendry
Apr 24, 1991·Brain Research. Developmental Brain Research·D ThomasB Boilly
Sep 19, 1991·Brain Research. Developmental Brain Research·M A Riva, I Mocchetti
Oct 1, 1992·Brain Research. Molecular Brain Research·M A RivaI Mocchetti
Mar 1, 1994·Brain Research. Molecular Brain Research·J T HendersonJ C Roder
Feb 1, 1994·Brain Research. Molecular Brain Research·N ItohT Kawasaki
Dec 1, 1993·Progress in Neurobiology·M Sensenbrenner
Aug 1, 1988·Molecular and Cellular Endocrinology·A Logan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.