The broader economic impact of vaccination: reviewing and appraising the strength of evidence

BMC Medicine
Mark JitJoanne Yoong

Abstract

Microeconomic evaluations of public health programmes such as immunisation typically only consider direct health benefits and medical cost savings. Broader economic benefits around childhood development, household behaviour, and macro-economic indicators are increasingly important, but the evidence linking immunization to such benefits is unclear. A conceptual framework of pathways between immunisation and its proposed broader economic benefits was developed through expert consultation. Relevant articles were obtained from previous reviews, snowballing, and expert consultation. Articles were associated with one of the pathways and quality assessed using modified Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. We found 20 studies directly relevant to one or more pathways. Evidence of moderate quality from experimental and observational studies was found for benefits due to immunisation in improved childhood physical development, educational outcomes, and equity in distribution of health gains. Only modelling evidence or evidence outside the immunization field supports extrapolating these benefits to household economic behaviour and macro-economic indicators. Innovative use of experimental and...Continue Reading

References

Apr 30, 2003·Health Economics·David BishaiMehrab Ali Khan
Apr 7, 2005·Nature Medicine·Stanley A Plotkin
Apr 13, 2005·Scandinavian Journal of Public Health·Rainer SauerbornMichael Lanzer
Nov 12, 2005·BMJ : British Medical Journal·Tessa Tan-Torres EdejerDavid B Evans
Oct 5, 2007·Proceedings of the National Academy of Sciences of the United States of America·David E Bloom, David Canning
May 21, 2008·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Ralph P InsingaEvan R Myers
Jul 29, 2008·Social Science & Medicine·Joanna CoastPaula Lorgelly
Dec 10, 2009·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Marcus Richard Keogh-BrownPhilippe Beutels
Mar 11, 2010·JAMA : the Journal of the American Medical Association·Mark LoebStephen D Walter
Aug 24, 2010·Clinical Therapeutics·Waka Anthony UdeziOmoyeme Oluwatosin Ihimekpen
Sep 25, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·J Jaime CaroUNKNOWN ISPOR-SMDM Modeling Good Research Practices Task Force
Mar 28, 2013·BMC Medicine·Don HusereauUNKNOWN CHEERS Task Force
Apr 16, 2013·Lancet·Zulfiqar A BhuttaUNKNOWN Lancet Diarrhoea and Pneumonia Interventions Study Group
Nov 23, 2013·Lancet·Karin StenbergUNKNOWN Study Group for the Global Investment Framework for Women's Children's Health
Aug 20, 2014·Proceedings of the National Academy of Sciences of the United States of America·Till BärnighausenJennifer Carroll O'Brien
Sep 24, 2014·BMC Health Services Research·Katherine Leach-KemonAnnie Haakenstad
Jun 1, 2005·The American Economic Review·Rodrigo R Soares

❮ Previous
Next ❯

Citations

Nov 26, 2015·Vaccine·Natasha de Francisco ShapovalovaRaymond Hutubessy
Oct 11, 2016·Neurologic Clinics·David S YoungerSally Guttmacher
Nov 3, 2016·Tropical Medicine & International Health : TM & IH·Tharani LoganathanStéphane Verguet
Oct 25, 2016·Vaccine·Mark DohertyDavid Prado-Cohrs
Feb 3, 2016·Applied Health Economics and Health Policy·Mark Jit, Raymond Hutubessy
Nov 1, 2017·PloS One·Elizabeth T Cafiero-FonsecaDavid E Bloom
May 23, 2018·Journal of Market Access & Health Policy·Baudouin Standaert, Rino Rappuoli
May 23, 2018·Journal of Market Access & Health Policy·Baudouin Standaert, Rino Rappuoli
Nov 15, 2019·The Pediatric Infectious Disease Journal·David E BloomAndrew Stawasz
Jan 7, 2017·BioMed Research International·Ingeborg M van der PuttenMickael Hiligsmann
Jun 6, 2017·Global Health Action·Stine BybergUlla Kou Griffiths
Apr 30, 2019·Transactions of the Royal Society of Tropical Medicine and Hygiene·Peter Austin Morton NtendaMfundi President Stam Motsa
Mar 22, 2020·The European Respiratory Journal·Nebiat GebreselassieMatteo Zignol
Sep 5, 2017·Bulletin of the World Health Organization·Sachiko OzawaDamian Walker
Mar 5, 2020·Journal of Market Access & Health Policy·Baudouin StandaertSharon Zhang
Jan 16, 2020·International Journal for Equity in Health·Allison PortnoyMark Jit
Oct 13, 2020·Vaccine·Alejandro E MaciasHongjie Yu
Nov 1, 2020·Vaccines·Jeroen LuytenPhilippe Beutels
Mar 9, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Enoch KungAlec Morton
Jul 25, 2020·Vaccine·Lois A Privor-DummUNKNOWN International Council on Adult Immunization
May 18, 2021·Vaccine: X·Simon BrasselLotte Steuten
Jun 11, 2021·Bulletin of the World Health Organization·Adnan A HyderPaul Ndebele
Sep 24, 2021·Applied Health Economics and Health Policy·Eleanor BellLotte Steuten

❮ Previous
Next ❯

Software Mentioned

GRADE
Cochrane

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Epidemiology and Community Health
Holger SchünemannFaruque Ahmed
Journal of Evidence-based Medicine
Gabrielle Goldet, Jeremy Howick
Journal of Psychosomatic Research
G E Simon, D J Katzelnick
© 2021 Meta ULC. All rights reserved