Abstract
Nearly 1% of Canadians are infected with the hepatitis C virus (HCV). Simulation analyses have suggested that HCV will place an increasing burden on the health care system as the infected population ages, but supportive clinical data are limited. To study temporal trends in HCV-related hospitalizations and predictors of increased health care utilization from a Canadian population-based perspective. An administrative hospitalization database from the Calgary Health Region was used to identify patients who were admitted for HCV between 1994 and 2004. The primary outcomes were liver-related HCV hospitalizations, length of stay, hospital costs and in-hospital mortality. Average annual growth rates in outcomes were calculated and subgroup analyses were conducted according to age, sex and HIV/HCV coinfection status. Between 1994 and 2004, there were 4002 HCV-related hospitalizations; 22% were liver-related. Liver-related hospitalizations, lengths of stay and in-hospital mortality increased approximately fourfold or an average of 15% to 18% annually (P<0.0005). Patients aged 40 to 59 years and HIV/HCV coinfected patients experienced the largest average annual growth rates (19% to 27% and 30% to 40%, respectively; P<0.0005), reflecting...Continue Reading
Citations
Dec 17, 2009·Journal of Viral Hepatitis·A N AnanthakrishnanK Saeian
Jan 26, 2011·BMC Public Health·Heather F GiddingMatthew G Law
Jul 12, 2016·CMAJ Open·Edward NgClaudia Sanmartin
Aug 10, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rhiannon KamstraChristina Greenaway
May 30, 2020·Journal of Clinical Medicine·Alejandro Alvaro-MecaSalvador Resino
Jun 7, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nadine KronfliUNKNOWN Canadian Coinfection Cohort Study Investigators
Dec 8, 2009·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Diana I BrixnerTarek I Hassanein
Jul 1, 2010·Epidemiology and Infection·S A McDonaldD J Goldberg
Jul 11, 2013·PharmacoEconomics·Stuart J TurnerJoseph A Paladino
Apr 7, 2015·CMAJ Open·Robert P MyersRobert J Hilsden
Oct 9, 2014·CMAJ Open·Dena L SchanzerLisa M Lix
Sep 13, 2015·BMC Gastroenterology·Jack X Q PangRobert P Myers
Jan 24, 2018·PloS One·Shelly BolotinTony Mazzulli
Nov 7, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Cameron SikaviSammy Saab
Oct 11, 2014·BMC Infectious Diseases·Christine U OramasionwuChristopher R Frei
Mar 31, 2012·Journal of Medical Economics·Antoine C El KhouryHomie Razavi
May 15, 2015·HIV Clinical Trials·Man Wah YeungMarina B Klein
Apr 24, 2014·PloS One·Jack X Q PangRobert P Myers
Dec 5, 2019·CMAJ Open·Nadine KronfliJoseph Cox
Feb 27, 2010·Digestive Diseases and Sciences·Ramsey CheungGurkirpal Singh
Oct 13, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Robert P MyersHude Quan
Aug 1, 2014·CMAJ Open·Jim YoungMarina B Klein