The burden of hepatitis C virus infection is growing: a Canadian population-based study of hospitalizations from 1994 to 2004.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
Robert P MyersAbdel Aziz Shaheen

Abstract

Nearly 1% of Canadians are infected with the hepatitis C virus (HCV). Simulation analyses have suggested that HCV will place an increasing burden on the health care system as the infected population ages, but supportive clinical data are limited. To study temporal trends in HCV-related hospitalizations and predictors of increased health care utilization from a Canadian population-based perspective. An administrative hospitalization database from the Calgary Health Region was used to identify patients who were admitted for HCV between 1994 and 2004. The primary outcomes were liver-related HCV hospitalizations, length of stay, hospital costs and in-hospital mortality. Average annual growth rates in outcomes were calculated and subgroup analyses were conducted according to age, sex and HIV/HCV coinfection status. Between 1994 and 2004, there were 4002 HCV-related hospitalizations; 22% were liver-related. Liver-related hospitalizations, lengths of stay and in-hospital mortality increased approximately fourfold or an average of 15% to 18% annually (P<0.0005). Patients aged 40 to 59 years and HIV/HCV coinfected patients experienced the largest average annual growth rates (19% to 27% and 30% to 40%, respectively; P<0.0005), reflecting...Continue Reading

Citations

Aug 10, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rhiannon KamstraChristina Greenaway
Jun 7, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nadine KronfliUNKNOWN Canadian Coinfection Cohort Study Investigators
Dec 8, 2009·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Diana I BrixnerTarek I Hassanein
Jul 1, 2010·Epidemiology and Infection·S A McDonaldD J Goldberg
Jul 11, 2013·PharmacoEconomics·Stuart J TurnerJoseph A Paladino
Jan 24, 2018·PloS One·Shelly BolotinTony Mazzulli
Nov 7, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Cameron SikaviSammy Saab
Mar 31, 2012·Journal of Medical Economics·Antoine C El KhouryHomie Razavi
Oct 13, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Robert P MyersHude Quan

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