The burden of hepatorenal syndrome among commercially insured and Medicare patients in the United States

Current Medical Research and Opinion
J Bradford RiceKhurram Jamil

Abstract

This study evaluated the characteristics, healthcare resource utilization (HCRU), and costs, from the payer perspective, of hepatorenal syndrome (HRS) patients covered by commercial and Medicare insurance. Mortality was assessed as a secondary outcome. Patients were identified from claims databases of commercially insured patients (OptumHealth Care Solutions Inc.) in 1998-2014 and Medicare beneficiaries in 2009-2013 (5% Standard Analytic Files). At the time of their first inpatient admission ("index date") with an HRS diagnosis (ICD-9 code 572.4), commercially insured patients must be aged 18-64 and Medicare patients must be aged 65 and older. A total of 784 commercially insured and 1061 Medicare HRS patients met the sample selection criteria. Patients were disproportionately male (commercial: 63.0%; Medicare: 57.9%) with a mean age of 54.1 among commercially insured and 74.1 among Medicare patients. Within the first 30 days, the average hospital length of stay (LOS) was 12.3 days among commercially insured and 10.8 days among Medicare patients. Based on Kaplan-Meier analyses, 36% of commercially insured and 26% of Medicare patients were readmitted within the next 30 days. During follow-up, many patients received dialysis (comm...Continue Reading

References

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Citations

Mar 27, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jessica L MellingerAnna S F Lok
Sep 13, 2019·The Cochrane Database of Systematic Reviews·Lawrence Mj BestKurinchi Selvan Gurusamy
Aug 25, 2020·Journal of Clinical and Translational Hepatology·Raseen Tariq, Ashwani K Singal
Apr 19, 2019·Clinical Journal of the American Society of Nephrology : CJASN·Claire FrancozMitra K Nadim
Mar 23, 2021·Gastroenterología y hepatología·Alana Zulian TerresJonathan Soldera
Sep 26, 2020·European Journal of Gastroenterology & Hepatology·Michael MakarAnish Vinit Patel

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