Abstract
Few innovations in medicine have so convincingly and expeditiously improved patient outcomes more than the development of the left ventricular assist device (LVAD). Where optimal pharmacotherapy once routinely failed those with end-stage disease, the LVAD now offers considerable hope for the growing advanced heart failure population. Despite improvements in mortality, however, mechanical circulatory support is not without its limitations. Those supported with an LVAD are at increased risk of several complications, including infection, bleeding, stroke and arrhythmic events. While once considered benign, ventricular arrhythmias in the LVAD patient are being increasingly recognised for their deleterious influence on patient morbidity and quality of life. In addition, the often multifactorial aetiology to these episodes makes treatment difficult and optimal therapeutic management controversial. Novel strategies are clearly needed to better predict, prevent, and eradicate these arrhythmias in order to allow future generations of heart failure patients to reap the full benefits of LVAD implantation.
Citations
Dec 24, 2018·Journal of Cardiovascular Electrophysiology·Mauricio Sendra-Ferrer, Mario D Gonzalez
Apr 5, 2019·Circulation·Rakesh GopinathannairKristen K Patton
Nov 27, 2019·Current Heart Failure Reports·Jacinthe BouletAnique Ducharme
Feb 12, 2020·Artificial Organs·Jonathan S GordonVakhtang Tchantchaleishvili
Sep 12, 2018·The Western Journal of Emergency Medicine·Paul TrinqueroJane E Wilcox
Sep 12, 2018·International Anesthesiology Clinics·Vidya K Rao, Albert Tsai
May 16, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ahmed ElkaryoniAlan P Wimmer
Jul 9, 2016·Journal of Cardiothoracic Surgery·Ameeta YakshNatasja M S de Groot
Mar 25, 2020·Current Opinion in Cardiology·Joan A MaradeyPrashant D Bhave
Apr 1, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jonathan GrinsteinNir Uriel
Dec 4, 2020·Journal of Cardiovascular Electrophysiology·Angeliki DarmaVincent Galand
Nov 3, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Alejandro LemorJennifer Cowger
Nov 3, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jonathan GrinsteinNir Uriel
May 11, 2019·The American Journal of Emergency Medicine·Brit LongWilliam Brady
Apr 12, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Michael R RehornJonathan P Piccini
Jun 19, 2021·Journal of Arrhythmia·Nicolò SistiMatteo Cameli