PMID: 9420776Mar 1, 1995Paper

The Canadian exercise technetium 99m-labeled teboroxime single-photon emission computed tomographic study. Canadian Exercise Teboroxime SPECT Study Investigators

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
R J BurnsL Daigneault

Abstract

99mTc-labeled teboroxime undergoes rapid washout from the myocardium. For this reason, its use has been favored in conjunction with pharmacologic stress, which enables patient positioning before tracer administration, and multidetector single-photon emission computed tomography (SPECT), which enables rapid acquisition. We evaluated treadmill exercise 99mTc-labeled teboroxime SPECT with single-detector systems for the detection of coronary artery disease. Treadmill exercise 99mTc-labeled teboroxime SPECT was compared with analogous 201Tl-labeled imaging in 108 patients. Teboroxime was injected first during exercise and then at rest. Nine myocardial segments per study were scored with respect to uptake of activity during stress and at rest (teboroxime) or after redistribution (201Tl). Perfusion was defined as normal, reversible, or fixed. Overall agreement of 201Tl versus teboroxime segmental perfusion (normal vs abnormal) was 772/961 (80.3%; chi 2 = 258; p < 0.001; kappa = 0.51) or (normal vs reversible vs fixed) 711/961 (74.0%; chi 2 = 296; p < 0.001; kappa = 0.42). Fifty-six patients also underwent selective coronary angiography. Stenoses greater than 50% of lumenal diameter were drawn on individualized coronary artery diagram...Continue Reading

References

Mar 1, 1991·American Heart Journal·A S IskandrianJ Mercuro
Oct 16, 1990·The American Journal of Cardiology·L L Johnson, D W Seldin

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Citations

Mar 18, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Xiao-Ying XiWei Fang

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