PMID: 22583406May 16, 2012Paper

The cancer preventive effects of edible mushrooms

Anti-cancer Agents in Medicinal Chemistry
Tongtong XuJoshua D Lambert

Abstract

An increasing body of scientific literature suggests that dietary components may exert cancer preventive effects. Tea, soy, cruciferous vegetables and other foods have been investigated for their cancer preventive potential. Some non-edible mushrooms like Reishi (Ganoderma lucidum) have a history use, both alone and in conjunction with standard therapies, for the treatment of various diseases including cancer in some cultures. They have shown efficacy in a number of scientific studies. By comparison, the potential cancer preventive effects of edible mushrooms have been less well-studied. With similar content of putative effective anticancer compounds such as polysaccharides, proteoglycans, steroids, etc., one might predict that edible mushrooms would also demonstrate anticancer and cancer preventive activity. In this review, available data for five commonly-consumed edible mushrooms: button mushrooms (Agaricus bisporus), A. blazei, oyster mushrooms (Pleurotus ostreatus), shiitake mushrooms (Lentinus edodes), and maitake (Grifola frondosa) mushrooms is discussed. The results of animal model and human intervention studies, as well as supporting in vitro mechanistic studies are critically evaluated. Weaknesses in the current data ...Continue Reading

Citations

Oct 18, 2015·Nutrition Research·Nopporn ThangthaengBarbara Shukitt-Hale
Mar 13, 2016·Food & Nutrition Research·Ana B BarrosTito Fernandes
May 29, 2014·Journal of Basic Microbiology·Dong-Ze LiuGang Liu
Sep 26, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hong-Ji LiYing-Chun Jiao
Aug 15, 2014·The Journal of Antibiotics·Dong-Ze LiuGang Liu
Jan 26, 2017·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Mirosław MleczekAnna Budka
Nov 23, 2017·Anais Da Academia Brasileira De Ciências·Elisabeth WisbeckSandra A Furlan
Feb 20, 2016·International Journal of Oncology·Takamitsu ShimizuRikiishi Hidemi
Apr 5, 2020·International Journal of Molecular Sciences·Ines AmaraVittorio Calabrese
Sep 18, 2021·Scientific Reports·William J BehofWellington Pham

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