PMID: 3746151Jul 1, 1986Paper

The cardiointegram: detection of coronary artery disease in males with chest pain and a normal resting electrocardiogram

Journal of Electrocardiology
L E TeichholzM H Ellestad

Abstract

The cardiointegram is a non-invasive technique for the analysis of the electrical signals of the heart obtained by a transformation of the voltage vs. time format by a series of integrations. This multicenter study compares the results of the cardiointegram with coronary arteriography in 140 male patients with chest pain and a normal resting electrocardiogram. The cardiointegram was determined on two resting complexes of Leads I, II, V4, V5 and V6 and called abnormal if greater than or equal to four of ten complexes were abnormal, i.e., fell outside of a previously determined template of normality. The sensitivity was 73% and specificity was 78% for the diagnosis of occlusive coronary artery disease. When greater than or equal to five of ten abnormal complexes were used as the cut-off for an abnormal test and "equivocal" results (four of ten abnormal, n = 18) were excluded from analysis there was a sensitivity of 69% and specificity of 88%. Thirty-seven of 38 patients (97%) with an abnormal cardiointegram and a positive exercise stress test had coronary artery disease. Thus, the cardiointegram appears to be a useful non-invasive test for the detection of coronary artery disease in males with chest pain and a normal resting elec...Continue Reading

References

Jul 31, 1975·The New England Journal of Medicine·B J McNeilS J Adelstein
May 26, 1977·The American Journal of Cardiology·P L McHenry
Sep 1, 1976·Annals of Internal Medicine·N GoldschlagerK Cohn
Sep 1, 1983·The New England Journal of Medicine·A RozanskiH J Swan
Jan 1, 1982·Medical Decision Making : an International Journal of the Society for Medical Decision Making·T PoynardJ P Etienne

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Citations

Nov 1, 1988·Journal of Medical Engineering & Technology·S M Maas, J Wickham
Apr 1, 1989·Pacing and Clinical Electrophysiology : PACE·S AbboudR J Cohen

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