PMID: 11932574Apr 5, 2002Paper

The cardiospecificity of the third-generation cTnT assay after exercise-induced muscle damage

Medicine and Science in Sports and Exercise
Robert ShaveDavid Gaze

Abstract

The purpose of the present study was to examine the cardiospecificity of cTnI and the new third-generation cTnT assay, in the presence of exercise-induced muscle damage in highly trained individuals, and to examine the impact of a maximal-ramping treadmill test on cardiac function. Eight highly trained male triathletes (mean +/- SD; age: 29 +/- 9 yr; height: 1.79 +/- 0.10 m; body mass: 77 +/- 10 kg; .VO(2max): 67.4 +/- 6.3 mL.kg(-1).min(-1)) completed two bouts of exercise. On the first occasion, subjects completed a maximal-ramping treadmill test. On a separate occasion, the subjects completed 30 min of downhill running (15% gradient) at a speed equivalent to 70% of maximal running velocity attained during the maximal-ramping treadmill test. All subjects were assessed using ECG, echocardiography, and blood analysis. Measurements were taken at rest, immediately after, and 48 h postexercise for each bout of exercise. Echocardiographic analysis was used to determine left ventricular systolic and diastolic function. Blood samples were analyzed for markers of myocyte damage. Echocardiographic results indicated normal left ventricular function before and after both exercise bouts. Total CK and CKMB were significantly elevated 48 h a...Continue Reading

References

Jul 1, 1975·The Journal of Clinical Investigation·W GrossmanL P McLaurin
Mar 1, 1991·Journal of Applied Physiology·J L VanoverscheldeJ M Detry
Dec 1, 1987·Circulation·P S DouglasN Reichek
Apr 1, 1987·International Journal of Sports Medicine·K NiemeläJ Takkunen
Aug 1, 1993·Sports Medicine·W J Rowe
Aug 15, 1996·The American Journal of Cardiology·L LaslettR Lind
May 1, 1996·International Journal of Sports Medicine·A BonettiG Tredici
Oct 24, 1997·Journal of Applied Physiology·S SorichterB Puschendorf
Jun 19, 1998·British Journal of Sports Medicine·S SorichterJ F Glatz
Jun 22, 2000·Medicine and Science in Sports and Exercise·G P WhyteW J McKenna

❮ Previous
Next ❯

Citations

Dec 29, 2017·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·A PerettiG Vignati
Jan 26, 2011·Journal of Cardiovascular Disease Research·Gamela NasrAlaa Saad
Feb 8, 2014·Medicine and Science in Sports and Exercise·Philip AagaardFrieder Braunschweig
Jun 13, 2014·Clinical Physiology and Functional Imaging·Caroline Le GoffJean-Louis Croisier
Oct 30, 2014·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Chan-Ho ParkYi-Sub Kwak
Oct 8, 2011·Omics : a Journal of Integrative Biology·Nathália Maria ResendeL C Cameron

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.