The cascading effects of human food on hibernation and cellular aging in free-ranging black bears

Scientific Reports
Rebecca KirbyJonathan N Pauli

Abstract

Human foods have become a pervasive subsidy in many landscapes, and can dramatically alter wildlife behavior, physiology, and demography. While such subsidies can enhance wildlife condition, they can also result in unintended negative consequences on individuals and populations. Seasonal hibernators possess a remarkable suite of adaptations that increase survival and longevity in the face of resource and energetic limitations. Recent work has suggested hibernation may also slow the process of senescence, or cellular aging. We investigated how use of human foods influences hibernation, and subsequently cellular aging, in a large-bodied hibernator, black bears (Ursus americanus). We quantified relative telomere length, a molecular marker for cellular age, and compared lengths in adult female bears longitudinally sampled over multiple seasons. We found that bears that foraged more on human foods hibernated for shorter periods of time. Furthermore, bears that hibernated for shorter periods of time experienced accelerated telomere attrition. Together these results suggest that although hibernation may ameliorate cellular aging, foraging on human food subsidies could counteract this process by shortening hibernation. Our findings hig...Continue Reading

References

Jul 1, 1992·The Journal of Nutrition·A KoizumiR Weindruch
Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J MeyneR K Moyzis
May 8, 1981·Science·C P LymanE D Papafrangos
Mar 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·D W InouyeB D Inouye
Nov 23, 2000·Nature·T Finkel, N J Holbrook
Mar 10, 2001·Nature·H J HarlowP A Iaizzo
Jun 21, 2001·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·P J LeBlancJ S Ballantyne
May 10, 2002·Nucleic Acids Research·Richard M Cawthon
Jul 13, 2002·Trends in Biochemical Sciences·Thomas von Zglinicki
Jan 28, 2004·Nature·J Lindsay OaksAleem Ahmed Khan
May 17, 2006·Trends in Ecology & Evolution·Pat Monaghan, Mark F Haussmann
Dec 13, 2006·The American Journal of Clinical Nutrition·A Hope JahrenBenjamin Caballero
Feb 14, 2008·Proceedings. Biological Sciences·David GrémilletPeter G Ryan
Mar 28, 2009·Proceedings. Biological Sciences·Pierre BizePat Monaghan
Aug 1, 2009·Ageing Research Reviews·Jason Munshi-South, Gerald S Wilkinson
Oct 30, 2009·Trends in Endocrinology and Metabolism : TEM·Richard G Melvin, Matthew T Andrews
Apr 1, 2011·Proceedings. Biological Sciences·Christopher TurbillThomas Ruf
Jun 7, 2011·Ecological Applications : a Publication of the Ecological Society of America·Amanda D RodewaldDaniel P Shustack
Sep 17, 2011·Biology Letters·Christopher TurbillThomas Ruf
Nov 16, 2011·Biochemistry. Biokhimii︠a︡·Lei WangGuimei He
Feb 8, 2013·Biology Letters·Christopher TurbillClaudia Bieber
Oct 19, 2013·Ecology Letters·Daniel OroAlejandro Martínez-Abraín
Aug 16, 2014·Biological Reviews of the Cambridge Philosophical Society·Thomas Ruf, Fritz Geiser
Oct 31, 2014·Conservation Biology : the Journal of the Society for Conservation Biology·John G EwenJim J Groombridge
Feb 12, 2015·Oecologia·Seth D NewsomeStanley D Gehrt
Sep 8, 2015·Experimental Gerontology·Martijn HammersJan Komdeur
Jan 29, 2016·Biomolecular Concepts·Cheng-Wei Wu, Kenneth B Storey
Aug 19, 2016·The Journal of Experimental Biology·Franz HoelzlThomas Ruf
Aug 23, 2016·Ecology and Evolution·F Stephen DobsonJan O Murie
Jan 23, 2018·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Lorin A Neuman-LeeSusannah S French

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Citations

Aug 8, 2020·Animals : an Open Access Journal From MDPI·Abigail Gazzard, Philip J Baker
Aug 14, 2021·Molecular Ecology·Megan L PowerEmma C Teeling
Aug 27, 2021·Molecular Ecology·Florentin RemotJean-François Lemaitre

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