PMID: 2092358Nov 1, 1990Paper

The cellobiose permease of Escherichia coli consists of three proteins and is homologous to the lactose permease of Staphylococcus aureus

Research in Microbiology
J ReizerM H Saier

Abstract

The cellobiose (cel) operon of Escherichia coli was recently sequenced and shown to consist of five genes, celABCDF (Parker and Hall, 1990). We have shown that the CelA, CelB and CelC proteins possess amino acid sequences which are homologous to different domains of the lactose permease of Staphylococcus aureus. CelB corresponds to the integral membrane portion of the permease (IIcel) while CelC (IIIcel) and CelA (IVcel) correspond to the two cytoplasmic domains which appear to comprise the first and second phosphorylation sites in the permease, respectively. The cellobiose permease is the only one of several homologous sequenced permeases of the phosphoenolpyruvate:sugar phosphotransferase system which has its three known functional domains residing on distinct polypeptide chains.

References

Jan 30, 1990·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J W LengelerB M Wöhrl
Mar 1, 1988·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·M H SaierC A Lee
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W R Pearson, D J Lipman

❮ Previous
Next ❯

Citations

Nov 11, 2008·Protein Engineering, Design & Selection : PEDS·Fankroma M T KonéCharles Tellier
Sep 15, 2010·BMC Genomics·Dmitry A RodionovAndrei L Osterman
Oct 22, 2011·Microbial Cell Factories·Kambiz Morabbi HeraviJosef Altenbuchner
May 2, 2006·Journal of Molecular Biology·Anselm Erich OberholzerBernhard Erni
Apr 28, 2004·Biochemical and Biophysical Research Communications·Yu-Hui LinKin-Fu Chak
Dec 22, 2007·Research in Microbiology·Vicente MonederoJosef Deutscher
May 18, 2007·Progress in Biophysics and Molecular Biology·Ming Ren Yen, Milton H Saier
Jul 24, 2008·FEMS Microbiology Reviews·Knut JahreisFritz Titgemeyer
Oct 1, 1994·FEMS Microbiology Reviews·W M de Vos, E E Vaughan
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·M K Berlyn
Sep 1, 1993·Microbiological Reviews·P W PostmaG R Jacobson
Dec 1, 1993·Microbiological Reviews·M Riley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.