PMID: 6414085Aug 1, 1983Paper

The cellular and humoral basis of the immune response

Seminars in Arthritis and Rheumatism
E Yunis

Abstract

Class II molecules, called Ia molecules or DR, are expressed in macrophages, B lymphocytes, and activated T cells. Through these molecules, the B and T cells produce the immune response. Furthermore, this class of glycoproteins can serve as markers for the immune responses and their related disorders, ie, autoimmune disease. The new discoveries of the extended haplotypes, which include the genes for some proteins of the complement system and the Ia-like genes, make it possible to study the association of a chromatin section of chromosome 6 (seven centimorgans) with diseases.

References

Jan 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·Z L AwdehC A Alper
Aug 1, 1982·Clinical Immunology and Immunopathology·C A AlperE J Yunis

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Citations

Nov 1, 1987·Arthritis and Rheumatism·J E RichardsonE C Keystone

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